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Molecular epidemiology of merkel cell polyomavirus: evidence for geographically related variant genotypes.

Claire Martel-Jantin 1, 2 Claudia Filippone 2 Patricia Tortevoye 2 Philippe V Afonso 2 Edouard Betsem 3, 2 Stéphane Descorps-Declere 4 Jérôme T J Nicol 5, 6 Antoine Touzé 6, 5 Pierre Coursaget 6, 5 Maryse Crouzat 7 Nicolas Berthet 2 Olivier Cassar 2 Antoine Gessain 2, * 
* Corresponding author
1 Cellule Pasteur
2 EPVO (UMR_3569 / U-Pasteur_3) - Epidémiologie et Physiopathologie des Virus Oncogènes
3 Faculté de Médecine et des Sciences Biomédicales
4 Bioanalyse génomique (Plate-Forme)
5 UMR ISP - Infectiologie et Santé Publique
6 Faculté des Sciences Pharmaceutiques
7 Centre Hospitalier Territorial de Noumea
Abstract : Merkel cell polyomavirus (MCPyV) is linked to a cutaneous cancer mainly occurring in Caucasians. DNA from skin swabs of 255 adults, originating from the 5 continents, were subjected to MCPyV PCRs. Phylogenetic analyses demonstrate the existence of 5 major geographically related MCPyV genotypes (Europe/North America, Africa [sub-Saharan], Oceania, South America, and Asia/Japan).
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PASTEUR | UNIV-PARIS7 | AFRIQ | UNIV-TOURS | CNRS | INRA | INRAE | UNIV-PARIS | UP-SCIENCES | ANR | INFECTIOLOGIE-SANTE-PUBLIQUE

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Claire Martel-Jantin, Claudia Filippone, Patricia Tortevoye, Philippe V Afonso, Edouard Betsem, et al.. Molecular epidemiology of merkel cell polyomavirus: evidence for geographically related variant genotypes.. Journal of Clinical Microbiology, 2014, 52 (5), pp.1687-90. ⟨10.1128/JCM.02348-13⟩. ⟨pasteur-01370940⟩

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