Fitting a mixture model by expectation maximization to discover motifs in biopolymers, Proceedings of the 2nd International Conference on Intelligent Systems for Molecular Biology, pp.28-36, 1994. ,
Prospective study of Clostridium difficile infections in Europe with phenotypic and genotypic characterisation of the isolates, Clinical Microbiology and Infection, vol.13, issue.11, pp.1048-1057, 2007. ,
DOI : 10.1111/j.1469-0691.2007.01824.x
based on ribosomal RNA gene sequencing, FEMS Microbiology Letters, vol.175, issue.2, pp.261-266, 1999. ,
DOI : 10.1111/j.1574-6968.1999.tb13629.x
reveals a related set of conjugative transposons carrying a variety of accessory genes, Mobile Genetic Elements, vol.63, issue.1, pp.8-12, 2012. ,
DOI : 10.1093/nar/29.18.3742
Genomic analysis of the erythromycin resistance element Tn5398 from Clostridium difficile, Microbiology, vol.147, issue.10, pp.2717-2728, 2001. ,
DOI : 10.1099/00221287-147-10-2717
Emergence and global spread of epidemic healthcare-associated Clostridium difficile, Nature Genetics, vol.377, issue.1, pp.109-113 ,
DOI : 10.1093/molbev/msi103
Antimicrobial resistance in Clostridium difficile, International Journal of Antimicrobial Agents, vol.34, issue.6, pp.516-522, 2009. ,
DOI : 10.1016/j.ijantimicag.2009.09.012
Conjugal transfer of plasmid-borne multiple antibiotic resistance in Streptococcus faecalis var. zymogenes, J. Bacteriol, vol.117, pp.360-372, 1974. ,
Demonstration of Conjugative Transposon (Tn5397)-Mediated Horizontal Gene Transfer between Clostridium difficile and Enterococcus faecalis, Antimicrobial Agents and Chemotherapy, vol.54, issue.11, pp.4924-4926, 2010. ,
DOI : 10.1128/AAC.00496-10
Genetic analysis of a tetracycline resistance element from Clostridium difficile and its conjugal transfer to and from Bacillus subtilis, Journal of General Microbiology, vol.136, issue.7, pp.1343-1349, 1990. ,
DOI : 10.1099/00221287-136-7-1343
Behavior and target site selection of conjugative transposon Tn916 in two different strains of toxigenic Clostridium difficile, Appl. Environ. Microbiol, vol.78, pp.2147-2153, 2012. ,
Actin-specific ADP-ribosyltransferase produced by a Clostridium difficile strain, Infect. Immun, vol.56, pp.2299-2306, 1988. ,
The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome, Nature Genetics, vol.21, issue.7, pp.779-786, 2006. ,
DOI : 10.1038/ng1830
Genome walking by single-specific-primer polymerase chain reaction: SSP-PCR, Gene, vol.84, issue.1, pp.1-8, 1989. ,
DOI : 10.1016/0378-1119(89)90132-7
Transferable tetracycline resistance in Clostridium difficile., Antimicrobial Agents and Chemotherapy, vol.19, issue.6, pp.997-1003, 1981. ,
DOI : 10.1128/AAC.19.6.997
Multidrug resistance in European Clostridium difficile clinical isolates, Journal of Antimicrobial Chemotherapy, vol.66, issue.10, pp.2227-2234 ,
DOI : 10.1093/jac/dkr292
ErmB Determinants and Tn916-Like Elements in Clinical Isolates of Clostridium difficile, Antimicrobial Agents and Chemotherapy, vol.49, issue.6, pp.2550-2553, 2005. ,
DOI : 10.1128/AAC.49.6.2550-2553.2005
Comparative analysis of Clostridium difficile clinical isolates belonging to different genetic lineages and time periods, Journal of Medical Microbiology, vol.53, issue.11, pp.1129-1136, 2004. ,
DOI : 10.1099/jmm.0.45682-0
DNA sequence of the insertional hot spot of Tn916 in the Clostridium difficile genome and discovery of a Tn916-like element in an environmental isolate integrated in the same hot spot, FEMS Microbiology Letters, vol.192, issue.1, pp.15-20, 2000. ,
DOI : 10.1111/j.1574-6968.2000.tb09352.x
Clostridium difficile erm(B)-containing elements and the burden on the in vitro fitness, Journal of Medical Microbiology, vol.62, issue.Pt_9, pp.1461-1467, 2013. ,
DOI : 10.1099/jmm.0.057117-0
Influence of Transferable Genetic Determinants on the Outcome of Typing Methods Commonly Used for Enterococcus faecium, Journal of Clinical Microbiology, vol.41, issue.4, pp.1499-1506, 2003. ,
DOI : 10.1128/JCM.41.4.1499-1506.2003
Transferable Resistance to Clindamycin, Erythromycin, and Tetracycline in Clostridium difficile, Antimicrobial Agents and Chemotherapy, vol.23, issue.5, pp.784-786, 1983. ,
DOI : 10.1128/AAC.23.5.784
Velvet: Algorithms for de novo short read assembly using de Bruijn graphs, Genome Research, vol.18, issue.5, 2008. ,
DOI : 10.1101/gr.074492.107