HLA-Fatal attraction.

Frédéric Vély (1, 2) , Rachel Golub (3, 4) , Eric Vivier (2, 1)

1 Laboratoire d'Immunologie [Hôpital de la Conception - APHM]
2 CIML - Centre d'Immunologie de Marseille - Luminy
3 Cellule Pasteur
4 Lymphopoïèse (UMR_1223 / U1223 / U-Pasteur_4) - Lymphopoïèse

Open conformers of the non-classical and monomorphic major histocompatibility complex (MHC) class I molecule HLA-F are ligands for the activating receptor KIR3DS1 and trigger the activation of natural killer (NK) cells.

Mots clés: NK cells

Domaines: Immunologie

Frédéric Vély, Rachel Golub, Eric Vivier. HLA-Fatal attraction.. Nature Immunology, 2016, 17 (9), pp.1012-4. ⟨10.1038/ni.3541⟩. ⟨pasteur-01366312⟩