D. Sepulveda, P. Salaun, P. Maas, N. Andre, C. Panthier et al., SARs Do Not Impair Position-Dependent Expression of a kit/LacZ Transgene, Biochemical and Biophysical Research Communications, vol.211, issue.3, pp.735-741, 1995.
DOI : 10.1006/bbrc.1995.1874

M. S. Diamond, E. Mehlhop, T. Oliphant, and M. A. Samuel, The host immunologic response to West Nile encephalitis virus, Frontiers in Bioscience, vol.Volume, issue.14, pp.3024-3034, 2009.
DOI : 10.2741/3432

B. L. Fredericksen, B. C. Keller, J. Fornek, M. G. Katze, G. Jr et al., Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1, Journal of Virology, vol.82, issue.2, pp.609-616, 2008.
DOI : 10.1128/JVI.01305-07

G. Gribaudo, S. Ravaglia, M. Gaboli, M. Gariglio, R. Cavallo et al., Interferon-?? Inhibits the Murine Cytomegalovirus Immediate-Early Gene Expression by Down-Regulating NF-??B Activity, Virology, vol.211, issue.1, pp.251-260, 1995.
DOI : 10.1006/viro.1995.1398

E. B. Hayes and D. J. Gubler, West Nile Virus: Epidemiology and Clinical Features of an Emerging Epidemic in the United States, Annual Review of Medicine, vol.57, issue.1, pp.181-194, 2006.
DOI : 10.1146/annurev.med.57.121304.131418

A. Kajaste-rudnitski, T. Mashimo, M. P. Frenkiel, J. L. Guenet, M. Lucas et al., The 2',5'-Oligoadenylate Synthetase 1b Is a Potent Inhibitor of West Nile Virus Replication Inside Infected Cells, Journal of Biological Chemistry, vol.281, issue.8, pp.4624-4637, 2006.
DOI : 10.1074/jbc.M508649200

S. Kawamoto, H. Niwa, F. Tashiro, S. Sano, G. Kondoh et al., A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre-mediated recombination, FEBS Letters, vol.94, issue.3, pp.263-268, 2000.
DOI : 10.1016/S0014-5793(00)01338-7

H. Kristiansen, C. A. Scherer, M. Mcvean, S. P. Iadonato, S. Vends et al., Extracellular 2'-5' Oligoadenylate Synthetase Stimulates RNase L-Independent Antiviral Activity: a Novel Mechanism of Virus-Induced Innate Immunity, Journal of Virology, vol.84, issue.22, pp.11898-11904, 2010.
DOI : 10.1128/JVI.01003-10

H. Kristiansen, H. H. Gad, S. Eskildsen-larsen, P. Despres, and R. Hartmann, The Oligoadenylate Synthetase Family: An Ancient Protein Family with Multiple Antiviral Activities, Journal of Interferon & Cytokine Research, vol.31, issue.1, pp.41-47, 2011.
DOI : 10.1089/jir.2010.0107

J. Kubo, K. Yamanouchi, K. Naito, and H. Tojo, Expression of the gene of interest fused to the EGFP-expressing gene in transgenic mice drived from selected transgenic embryos, Journal of Experimental Zoology, vol.11, issue.7, pp.712-718, 2002.
DOI : 10.1002/jez.10163

J. K. Lim, A. Lisco, D. H. Mcdermott, L. Huynh, J. M. Ward et al., Genetic Variation in OAS1 Is a Risk Factor for Initial Infection with West Nile Virus in Man, PLoS Pathogens, vol.1, issue.2, 2009.
DOI : 10.1371/journal.ppat.1000321.s003

S. Linke, H. Ellerbrok, M. Niedrig, A. Nitsche, and G. Pauli, Detection of West Nile virus lineages 1 and 2 by real-time PCR, Journal of Virological Methods, vol.146, issue.1-2, pp.355-358, 2007.
DOI : 10.1016/j.jviromet.2007.05.021

K. J. Livak and T. D. Schmittgen, Analysis of relative gene expression data using real-time quantitative PCR and the 2(?Delta Delta C(T)) Method, pp.402-408, 2001.

M. Lucas, T. Mashimo, M. P. Frenkiel, D. Simon-chazottes, X. Montagutelli et al., Infection of mouse neurones by West Nile virus is modulated by the interferon-inducible 2'-5' oligoadenylate synthetase 1b protein, Immunology and Cell Biology, vol.8, issue.3, pp.230-236, 2003.
DOI : 10.1073/pnas.202448899

M. Malkinson, C. Banet, Y. Weisman, S. Pokamunski, R. King et al., Introduction of West Nile virus in the Middle East by Migrating White Storks, Emerging Infectious Diseases, vol.8, issue.4, pp.392-397, 2002.
DOI : 10.3201/eid0804.010217

D. Simon-chazottes, Transgenic expression of full-length 2???,5???-oligoadenylate synthetase 1b confers to BALB/c mice resistance against West Nile virus-induced encephalitis, Virology, vol.417, issue.1, pp.147-153, 2011.
DOI : 10.1016/j.virol.2011.05.018

URL : https://hal.archives-ouvertes.fr/pasteur-01325901

T. Mashimo, M. Lucas, D. Simon-chazottes, M. P. Frenkiel, X. Montagutelli et al., A nonsense mutation in the gene encoding 2'-5'-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory mice, Proc. Natl. Acad. Sci. U. S. A. 99, pp.11311-11316, 2002.
DOI : 10.1073/pnas.172195399

T. Mashimo, P. Glaser, M. Lucas, D. Simon-chazottes, P. E. Ceccaldi et al., Structural and functional genomics and evolutionary relationships in the cluster of genes encoding murine 2???,5???-oligoadenylate synthetases, Genomics, vol.82, issue.5, pp.537-552, 2003.
DOI : 10.1016/S0888-7543(03)00176-9

D. Matsuda, H. Sato, and L. E. Maquat, Studying Nonsense-Mediated mRNA Decay in Mammalian Cells, Methods Enzymol, vol.449, pp.177-201, 2008.
DOI : 10.1016/S0076-6879(08)02409-9

H. Niwa, K. Yamamura, and J. Miyazaki, Efficient selection for high-expression transfectants with a novel eukaryotic vector, Gene, vol.108, pp.193-199, 1991.

M. Okabe, M. Ikawa, K. Kominami, T. Nakanishi, and Y. Nishimune, ???Green mice??? as a source of ubiquitous green cells, FEBS Letters, vol.380, issue.3, pp.313-319, 1997.
DOI : 10.1016/S0014-5793(97)00313-X

A. A. Perelygin, S. V. Scherbik, I. B. Zhulin, B. M. Stockman, Y. Li et al., Positional cloning of the murine flavivirus resistance gene, Proceedings of the National Academy of Sciences, vol.99, issue.14, pp.9322-9327, 2002.
DOI : 10.1073/pnas.142287799

L. Qin, Y. Ding, D. R. Pahud, E. Chang, M. J. Imperiale et al., Inhibit Transgene Expression, Human Gene Therapy, vol.8, issue.17, pp.2019-2029, 1997.
DOI : 10.1089/hum.1997.8.17-2019

S. V. Scherbik, K. Kluetzman, A. A. Perelygin, and M. A. Brinton, Knock-in of the Oas1br allele into a flavivirus-induced disease susceptible mouse generates the resistant phenotype, Virology, vol.368, issue.2, pp.232-237, 2007.
DOI : 10.1016/j.virol.2007.08.017

S. V. Scherbik, B. M. Stockman, and M. A. Brinton, Differential Expression of Interferon (IFN) Regulatory Factors and IFN-Stimulated Genes at Early Times after West Nile Virus Infection of Mouse Embryo Fibroblasts, Journal of Virology, vol.81, issue.21, pp.12005-12018, 2007.
DOI : 10.1128/JVI.01359-07

Z. L. Xu, H. Mizuguchi, A. Ishii-watabe, E. Uchida, T. Mayumi et al., Optimization of transcriptional regulatory elements for constructing plasmid vectors, Gene, vol.272, issue.1-2, pp.149-156, 2001.
DOI : 10.1016/S0378-1119(01)00550-9

H. Yang, T. A. Bell, G. A. Churchill, and F. Pardo-manuel-de-villena, On the subspecific origin of the laboratory mouse, Nature Genetics, vol.175, issue.9, pp.1100-1107, 2007.
DOI : 10.1016/S0092-8240(89)80049-7