G. D. Brown, Hidden Killers: Human Fungal Infections, Science Translational Medicine, vol.4, issue.165, pp.10-1126, 2012.
DOI : 10.1126/scitranslmed.3004404

D. P. Kontoyiannis, Prospective Surveillance for Invasive Fungal Infections in Hematopoietic Stem Cell Transplant Recipients, 2001???2006: Overview of the Transplant???Associated Infection Surveillance Network (TRANSNET) Database, Clinical Infectious Diseases, vol.50, issue.8, pp.1091-1100, 2001.
DOI : 10.1086/651263

C. Garcia-vidal, A. Upton, K. A. Kirby, and K. A. Marr, Epidemiology of Invasive Mold Infections in Allogeneic Stem Cell Transplant Recipients: Biological Risk Factors for Infection According to Time after Transplantation, Clinical Infectious Diseases, vol.47, issue.8, pp.1041-1050, 2008.
DOI : 10.1086/591969

K. A. Marr, R. A. Carter, M. Boeckh, P. Martin, and L. Corey, Invasive aspergillosis in allogeneic stem cell transplant recipients: changes in epidemiology and risk factors, Blood, vol.100, issue.13, pp.4358-4366, 2002.
DOI : 10.1182/blood-2002-05-1496

R. E. Lewis and D. P. Kontoyiannis, Invasive aspergillosis in glucocorticoid-treated patients Medical mycology: official publication of the International Society for Human and, Animal Mycology, vol.47, pp.271-281, 1080.

O. Ibrahim-granet, In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis, BMC Microbiology, vol.10, issue.1, p.105, 2010.
DOI : 10.1186/1471-2180-10-105
URL : https://hal.archives-ouvertes.fr/pasteur-00934271

N. Grahl, In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis, PLoS Pathogens, vol.198, issue.7, 2011.
DOI : 10.1371/journal.ppat.1002145.s006

J. L. Hsu, Aspergillus fumigatus Invasion Increases with Progressive Airway Ischemia, PLoS ONE, vol.290, issue.10, p.77136, 2013.
DOI : 10.1371/journal.pone.0077136.s003

T. Takuma, K. Okada, Y. Uchida, A. Yamagata, and Y. Sawae, Invasive pulmonary aspergillosis resulting in respiratory failure during neutrophil recovery from postchemotherapy neutropenia in three patients with acute leukaemia, Journal of Internal Medicine, vol.64, issue.2, pp.173-177, 2002.
DOI : 10.1128/IAI.68.2.688-693.2000

R. Ben-ami, R. E. Lewis, K. Leventakos, and D. P. Kontoyiannis, Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites, Blood, vol.114, issue.26, pp.5393-5399, 2009.
DOI : 10.1182/blood-2009-07-231209

S. J. Blosser, B. Merriman, N. Grahl, D. Chung, and R. A. Cramer, Two C4-sterol methyl oxidases (Erg25) catalyse ergosterol intermediate demethylation and impact environmental stress adaptation in Aspergillus fumigatus, Microbiology, vol.160, issue.Pt_11, pp.2492-2506, 2014.
DOI : 10.1099/mic.0.080440-0

D. Chung, ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence, PLoS Pathogens, vol.155, issue.11, 2014.
DOI : 10.1371/journal.ppat.1004487.s010

N. Grahl, T. M. Dinamarco, S. D. Willger, G. H. Goldman, and R. A. Cramer, mitochondrial electron transport chain mediates oxidative stress homeostasis, hypoxia responses and fungal pathogenesis, Molecular Microbiology, vol.4, issue.1, pp.383-399, 2012.
DOI : 10.1111/j.1365-2958.2012.08034.x

S. D. Willger, Dsc Orthologs Are Required for Hypoxia Adaptation, Triazole Drug Responses, and Fungal Virulence in Aspergillus fumigatus, Eukaryotic Cell, vol.11, issue.12, pp.1557-156700252, 1128.
DOI : 10.1128/EC.00252-12

S. D. Willger, A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus, PLoS Pathogens, vol.8, issue.3, 2008.
DOI : 10.1371/journal.ppat.1000200.s001

A. Carvalho, Inflammation in aspergillosis: the good, the bad, and the therapeutic, Annals of the New York Academy of Sciences, vol.36, issue.1, pp.52-59, 2012.
DOI : 10.1111/j.1749-6632.2012.06754.x

R. G. Iannitti, Treg imbalance in murine cystic fibrosis is linked to indoleamine 2,3-dioxygenase deficiency but corrected by kynurenines American journal of respiratory and critical care medicine 187, pp.609-620, 2013.

B. Kim, The Interleukin-1alpha Precursor is Biologically Active and is Likely a Key Alarmin in the IL-1 Family of Cytokines, Frontiers in immunology, vol.4, issue.391, p.391, 2013.

H. K. Eltzschig and P. Carmeliet, Hypoxia and inflammation, The New England journal of medicine, vol.364, pp.656-665, 2011.

G. Y. Chen and G. Nunez, Sterile inflammation: sensing and reacting to damage, Nature Reviews Immunology, vol.464, issue.12, pp.826-837, 2010.
DOI : 10.1038/nri2873

P. Ghezzi, Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells, Cytokine, vol.3, issue.3, pp.189-194, 1991.
DOI : 10.1016/1043-4666(91)90015-6

S. Frohlich, J. Boylan, and P. Mcloughlin, Hypoxia-Induced Inflammation in the Lung, American Journal of Respiratory Cell and Molecular Biology, vol.48, issue.3, pp.271-279, 2013.
DOI : 10.1165/rcmb.2012-0137TR

C. R. Bonnett, E. J. Cornish, A. G. Harmsen, and J. B. Burritt, Early Neutrophil Recruitment and Aggregation in the Murine Lung Inhibit Germination of Aspergillus fumigatus Conidia, Infection and Immunity, vol.74, issue.12, pp.6528-6539, 2006.
DOI : 10.1128/IAI.00909-06

B. Bao, In Vivo Imaging and Quantification of Carbonic Anhydrase IX Expression as an Endogenous Biomarker of Tumor Hypoxia, PLoS ONE, vol.16, issue.11, p.50860, 2012.
DOI : 10.1371/journal.pone.0050860.s005

M. M. Mircescu, L. Lipuma, N. Van-rooijen, E. G. Pamer, and T. M. Hohl, Infection, The Journal of Infectious Diseases, vol.200, issue.4, pp.647-656, 2009.
DOI : 10.1086/600380

J. B. Robertson, C. C. Stowers, E. Boczko, and C. H. Johnson, Real-time luminescence monitoring of cell-cycle and respiratory oscillations in yeast, Proceedings of the National Academy of Sciences, vol.105, issue.46, pp.17988-17993, 2008.
DOI : 10.1073/pnas.0809482105

A. K. Caffrey, IL-1alpha Signaling Is Critical for Leukocyte Recruitment after Pulmonary Aspergillus fumigatus Challenge, PLoS pathogens, vol.11, 2015.

A. Jhingran, Compartment-Specific and Sequential Role of MyD88 and CARD9 in Chemokine Induction and Innate Defense during Respiratory Fungal Infection, PLOS Pathogens, vol.99, issue.1, 2015.
DOI : 10.1371/journal.ppat.1004589.s002

J. J. Haddad, Recombinant human interleukin (IL)-1 beta-mediated regulation of hypoxia-inducible factor-1 alpha (HIF-1 alpha) stabilization, nuclear translocation and activation requires an antioxidant/reactive oxygen species (ROS)-sensitive mechanism, European cytokine network 13, pp.250-260, 2002.

T. Hellwig-burgel, K. Rutkowski, E. Metzen, J. Fandrey, and W. Jelkmann, Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1, Blood, vol.94, pp.1561-1567, 1999.

P. Rider, The transcription of the alarmin cytokine interleukin-1 alpha is controlled by hypoxia inducible factors 1 and 2 alpha in hypoxic cells, Frontiers in Immunology, vol.3, issue.290, p.290, 2012.
DOI : 10.3389/fimmu.2012.00290

W. Zhang, Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1?? (IL-1??) in astrocyte cultures, Journal of Neuroimmunology, vol.174, issue.1-2, pp.63-73, 2006.
DOI : 10.1016/j.jneuroim.2006.01.014

C. A. Dinarello, A. Simon, and J. W. Van-der-meer, Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases, Nature Reviews Drug Discovery, vol.17, issue.8, pp.633-652, 2012.
DOI : 10.1038/nrd3800

A. De-luca, IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans, Proceedings of the National Academy of Sciences, vol.111, issue.9, pp.3526-3531, 2014.
DOI : 10.1073/pnas.1322831111

B. Fritzsching, Hypoxic Epithelial Necrosis Triggers Neutrophilic Inflammation via IL-1 Receptor Signaling in Cystic Fibrosis Lung Disease American journal of respiratory and critical care medicine, pp.10-1164, 2015.

K. E. Lee and M. C. Simon, SnapShot: Hypoxia-Inducible Factors, Cell, vol.163, issue.5, pp.1288-1288, 2015.
DOI : 10.1016/j.cell.2015.11.011

C. L. Chen, J. S. Chu, W. C. Su, S. C. Huang, and W. Lee, Hypoxia and metabolic phenotypes during breast carcinogenesis: expression of HIF-1??, GLUT1, and CAIX, Virchows Archiv, vol.268, issue.1, pp.53-61, 2010.
DOI : 10.1007/s00428-010-0938-0

J. Frangioni, In vivo near-infrared fluorescence imaging, Current Opinion in Chemical Biology, vol.7, issue.5, pp.626-634, 2003.
DOI : 10.1016/j.cbpa.2003.08.007

M. Zatovicova, Carbonic Anhydrase IX as an Anticancer Therapy Target: Preclinical Evaluation of Internalizing Monoclonal Antibody Directed to Catalytic Domain, Current Pharmaceutical Design, vol.16, issue.29, pp.3255-3263, 2010.
DOI : 10.2174/138161210793429832

Y. Lou, Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors, Cancer Research, vol.71, issue.9, pp.3364-3376, 2011.
DOI : 10.1158/0008-5472.CAN-10-4261
URL : https://hal.archives-ouvertes.fr/hal-00676367

I. Desbaillets, A. C. Diserens, N. Tribolet, M. F. Hamou, and E. G. Van-meir, Upregulation of Interleukin 8 by Oxygen-deprived Cells in Glioblastoma Suggests a Role in Leukocyte Activation, Chemotaxis, and Angiogenesis, The Journal of Experimental Medicine, vol.158, issue.8, pp.1201-1212, 1997.
DOI : 10.1172/JCI117450

A. Naldini, A. Pucci, and F. Carraro, HYPOXIA INDUCES THE EXPRESSION AND RELEASE OF INTERLEUKIN 1 RECEPTOR ANTAGONIST IN MITOGEN-ACTIVATED MONONUCLEAR CELLS, Cytokine, vol.13, issue.6, pp.334-3410842, 2001.
DOI : 10.1006/cyto.2001.0842

M. L. Hernandez, IL-1 receptor antagonist reduces endotoxin-induced airway inflammation in healthy volunteers, Journal of Allergy and Clinical Immunology, vol.135, issue.2, pp.379-385039, 2015.
DOI : 10.1016/j.jaci.2014.07.039

J. A. Frank, J. F. Pittet, C. Wray, and M. A. Matthay, Protection from experimental ventilator-induced acute lung injury by IL-1 receptor blockade, Thorax, vol.63, issue.2, pp.147-153079608, 2007.
DOI : 10.1136/thx.2007.079608

K. M. Shepardson, Myeloid Derived Hypoxia Inducible Factor 1-alpha Is Required for Protection against Pulmonary Aspergillus fumigatus Infection, PLoS Pathogens, vol.155, issue.9, 2014.
DOI : 10.1371/journal.ppat.1004378.s005

F. Meissner, Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease, Blood, vol.116, issue.9, pp.1570-1573, 2010.
DOI : 10.1182/blood-2010-01-264218

M. G. Schappi, V. Jaquet, D. C. Belli, and K. H. Krause, Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase, Seminars in Immunopathology, vol.288, issue.3, pp.255-271, 2008.
DOI : 10.1007/s00281-008-0119-2

R. Van-bruggen, Human NLRP3 inflammasome activation is Nox1-4 independent, Blood, vol.115, issue.26, pp.5398-5400, 2010.
DOI : 10.1182/blood-2009-10-250803

F. L. Van-de-veerdonk, Reactive oxygen species-independent activation of the IL-1?? inflammasome in cells from patients with chronic granulomatous disease, Proceedings of the National Academy of Sciences, vol.107, issue.7, pp.3030-3033, 2010.
DOI : 10.1073/pnas.0914795107

A. P. Knutsen and R. G. Slavin, Allergic Bronchopulmonary Aspergillosis in Asthma and Cystic Fibrosis, Clinical and Developmental Immunology, vol.164, issue.3, p.843763, 2011.
DOI : 10.1056/NEJM200003163421102

P. A. Greenberger, Allergic bronchopulmonary aspergillosis. The Journal of allergy and clinical immunology 110, pp.685-692, 2002.

A. P. Knutsen, Fungi and allergic lower respiratory tract diseases. The Journal of allergy and clinical immunology 129, pp.280-291, 2012.

J. L. Kreindler, Vitamin D3 attenuates Th2 responses to Aspergillus fumigatus mounted by CD4+ T cells from cystic fibrosis patients with allergic bronchopulmonary aspergillosis, Journal of Clinical Investigation, vol.120, issue.9, pp.3242-3254, 2010.
DOI : 10.1172/JCI42388DS1

E. V. Svirshchevskaya and V. P. Kurup, Immunotherapy of allergic bronchopulmonary aspergillosis a clinical and experimental approach, Frontiers in Bioscience, vol.8, issue.6, pp.92-101, 2003.
DOI : 10.2741/996

S. Bellocchio, Immunity to Aspergillus fumigatus: the basis for immunotherapy and vaccination. Medical mycology: official publication of the International Society for Human and Animal Mycology 43, pp.181-188, 2005.

E. P. Buddingh, Interferon-gamma Immunotherapy in a Patient With Refractory Disseminated Candidiasis, The Pediatric Infectious Disease Journal, vol.34, issue.12, pp.10-1097, 2015.
DOI : 10.1097/INF.0000000000000909

C. E. Delsing, Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series, BMC Infectious Diseases, vol.27, issue.5, pp.10-1186, 2014.
DOI : 10.1016/j.ijantimicag.2006.01.002

T. Lehrnbecher, Immunotherapy in Invasive Fungal Infection - Focus on Invasive Aspergillosis, Current Pharmaceutical Design, vol.19, issue.20, pp.3689-3712, 2013.
DOI : 10.2174/1381612811319200010

B. J. Kullberg, F. Van-de-veerdonk, and M. G. Netea, Immunotherapy, Current Opinion in Infectious Diseases, vol.27, issue.6, pp.511-516, 2014.
DOI : 10.1097/QCO.0000000000000105

C. Galiger, Assessment of Efficacy of Antifungals against Aspergillus fumigatus: Value of Real-Time Bioluminescence Imaging, Antimicrobial Agents and Chemotherapy, vol.57, issue.7, pp.3046-3059, 2013.
DOI : 10.1128/AAC.01660-12

B. Mehrad, T. A. Moore, and T. J. Standiford, Macrophage Inflammatory Protein-1?? Is a Critical Mediator of Host Defense Against Invasive Pulmonary Aspergillosis in Neutropenic Hosts, The Journal of Immunology, vol.165, issue.2, pp.962-968, 2000.
DOI : 10.4049/jimmunol.165.2.962

M. Brock, Bioluminescent Aspergillus fumigatus, a New Tool for Drug Efficiency Testing and In Vivo Monitoring of Invasive Aspergillosis, Applied and Environmental Microbiology, vol.74, issue.22, pp.7023-7035, 2008.
DOI : 10.1128/AEM.01288-08

V. Ntziachristos and R. Weissleder, Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation, Optics Letters, vol.26, issue.12, pp.893-895, 2001.
DOI : 10.1364/OL.26.000893

O. Ibrahim-granet, Phagocytosis and Intracellular Fate of Aspergillus fumigatus Conidia in Alveolar Macrophages, Infection and Immunity, vol.71, issue.2, pp.891-903, 2003.
DOI : 10.1128/IAI.71.2.891-903.2003

B. K. Sinha, D. P. Monga, and S. Prasad, A combination of Gomori-Grocott methenamine silver nitrate and hematoxylene and eosin staining technique for the demonstration of Candida albicans in tissue, Quad Sclavo Diagn, vol.24, pp.129-132, 1988.

S. K. Park, Hypoxia-Induced Gene Expression Occurs Solely through the Action of Hypoxia-Inducible Factor 1?? (HIF-1??): Role of Cytoplasmic Trapping of HIF-2??, Molecular and Cellular Biology, vol.23, issue.14, pp.4959-4971, 2003.
DOI : 10.1128/MCB.23.14.4959-4971.2003