D. Asante, L. Maccarthy-morrogh, A. Townley, M. Weiss, K. Katayama et al., A role for the Golgi matrix protein giantin in ciliogenesis through control of the localization of dynein-2, Journal of Cell Science, vol.126, issue.22, pp.5189-5197, 2013.
DOI : 10.1242/jcs.131664

D. Baron, K. Ralston, Z. Kabututu, and K. Hill, Functional genomics in Trypanosoma brucei identifies evolutionarily conserved components of motile flagella, Journal of Cell Science, vol.120, issue.3, pp.478-491, 2007.
DOI : 10.1242/jcs.03352

R. Behal, M. Miller, H. Qin, B. Lucker, A. Jones et al., Subunit Interactions and Organization of the Chlamydomonas reinhardtii Intraflagellar Transport Complex A Proteins, Journal of Biological Chemistry, vol.287, issue.15, pp.11689-11703, 2012.
DOI : 10.1074/jbc.M111.287102

M. Berriman, E. Ghedin, C. Hertz-fowler, G. Blandin, H. Renauld et al., The Genome of the African Trypanosome Trypanosoma brucei, Science, vol.309, issue.5733, pp.416-422, 2005.
DOI : 10.1126/science.1112642

S. Bhogaraju, L. Cajanek, C. Fort, T. Blisnick, K. Weber et al., Molecular Basis of Tubulin Transport Within the Cilium by IFT74 and IFT81, Science, vol.341, issue.6149, pp.1009-1012, 2013.
DOI : 10.1126/science.1240985

S. Bhogaraju, B. Engel, and E. Lorentzen, Intraflagellar transport complex structure and cargo interactions, Cilia, vol.2, issue.1, p.10, 2013.
DOI : 10.1186/2046-2530-2-10

O. Blacque, C. Li, P. Inglis, M. Esmail, G. Ou et al., The WD Repeat-containing Protein IFTA-1 Is Required for Retrograde Intraflagellar Transport, Molecular Biology of the Cell, vol.17, issue.12, pp.5053-5062, 2006.
DOI : 10.1091/mbc.E06-06-0571

M. Bonhivers, N. Landrein, M. Decossas, and D. Robinson, A monoclonal antibody marker for the exclusion-zone filaments of Trypanosoma brucei, Parasites & Vectors, vol.1, issue.1, 2008.
DOI : 10.1186/1756-3305-1-21

URL : https://hal.archives-ouvertes.fr/hal-00300511

C. Bredrup, S. Saunier, M. Oud, T. Fiskerstrand, A. Hoischen et al., Ciliopathies with Skeletal Anomalies and Renal Insufficiency due to Mutations in the IFT-A Gene WDR19, The American Journal of Human Genetics, vol.89, issue.5, pp.634-643, 2011.
DOI : 10.1016/j.ajhg.2011.10.001

L. Briggs, J. Davidge, B. Wickstead, M. Ginger, and K. Gull, More than one way to build a flagellum: comparative genomics of parasitic protozoa, Current Biology, vol.14, issue.15, pp.611-612, 2004.
DOI : 10.1016/j.cub.2004.07.041

J. Buisson, N. Chenouard, T. Lagache, T. Blisnick, J. Olivo-marin et al., Intraflagellar transport proteins cycle between the flagellum and its base, Journal of Cell Science, vol.126, issue.1, pp.327-338, 2013.
DOI : 10.1242/jcs.117069

N. Chenouard, J. Buisson, I. Bloch, P. Bastin, and J. Olivo-marin, Curvelet analysis of kymograph for tracking bi-directional particles in flurescence microscopy images, 17th IEEE International Conference on Image Processing, pp.3657-3660, 2010.

D. Dacheux, N. Landrein, M. Thonnus, G. Gilbert, A. Sahin et al., A MAP6-Related Protein Is Present in Protozoa and Is Involved in Flagellum Motility, PLoS ONE, vol.123, issue.Pt 3, 2012.
DOI : 10.1371/journal.pone.0031344.s008

URL : https://hal.archives-ouvertes.fr/hal-01101397

N. Dagoneau, M. Goulet, D. Genevieve, Y. Sznajer, J. Martinovic et al., DYNC2H1 Mutations Cause Asphyxiating Thoracic Dystrophy and Short Rib-Polydactyly Syndrome, Type III, The American Journal of Human Genetics, vol.84, issue.5, pp.706-711, 2009.
DOI : 10.1016/j.ajhg.2009.04.016

E. Davis, Q. Zhang, Q. Liu, B. Diplas, L. Davey et al., TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum, Nature Genetics, vol.36, issue.3, pp.189-196, 2011.
DOI : 10.1073/pnas.0610155104

H. Dawe, H. Farr, N. Portman, M. Shaw, and K. Gull, The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis, Journal of Cell Science, vol.118, issue.23, pp.5421-5430, 2005.
DOI : 10.1242/jcs.02659

L. Dibella and S. King, Dynein motors of the Chlamydomonas flagellum, Int Rev Cytol, vol.210, pp.227-268, 2001.
DOI : 10.1016/S0074-7696(01)10007-0

D. Doroquez, C. Berciu, J. Anderson, P. Sengupta, and D. Nicastro, A high-resolution morphological and ultrastructural map of anterior sensory cilia and glia in Caenorhabditis elegans, 1948.

P. Duquesnoy, E. Escudier, L. Vincensini, J. Freshour, A. Bridoux et al., Loss-of-Function Mutations in the Human Ortholog of Chlamydomonas reinhardtii ODA7 Disrupt Dynein Arm Assembly and Cause Primary Ciliary Dyskinesia, The American Journal of Human Genetics, vol.85, issue.6, pp.890-896, 2009.
DOI : 10.1016/j.ajhg.2009.11.008

M. Durand-dubief, L. Kohl, and P. Bastin, Efficiency and specificity of RNA interference generated by intra- and intermolecular double stranded RNA in Trypanosoma brucei, Molecular and Biochemical Parasitology, vol.129, issue.1, pp.11-21, 2003.
DOI : 10.1016/S0166-6851(03)00071-9

R. Finn, A. Bateman, J. Clements, P. Coggill, R. Eberhardt et al., Pfam: the protein families database, Nucleic Acids Research, vol.42, issue.D1, pp.222-230, 2014.
DOI : 10.1093/nar/gkt1223

URL : https://hal.archives-ouvertes.fr/hal-01294685

J. Franklin and E. Ullu, Biochemical analysis of PIFTC3, the Trypanosoma brucei orthologue of nematode DYF-13, reveals interactions with established and putative intraflagellar transport components, Molecular Microbiology, vol.178, pp.173-186, 2010.
DOI : 10.1111/j.1365-2958.2010.07322.x

C. Gilissen, H. Arts, A. Hoischen, L. Spruijt, D. Mans et al., Exome REFERENCES, 2010.

S. Absalon, T. Blisnick, M. Bonhivers, L. Kohl, N. Cayet et al., Flagellum elongation is required for correct structure, orientation and function of the flagellar pocket in Trypanosoma brucei, Journal of Cell Science, vol.121, issue.22, pp.3704-3716, 2008.
DOI : 10.1242/jcs.035626

URL : https://hal.archives-ouvertes.fr/hal-00426339

S. Absalon, T. Blisnick, L. Kohl, G. Toutirais, G. Dore et al., Intraflagellar Transport and Functional Analysis of Genes Required for Flagellum Formation in Trypanosomes, Molecular Biology of the Cell, vol.19, issue.3, pp.929-944, 2008.
DOI : 10.1091/mbc.E07-08-0749

URL : https://hal.archives-ouvertes.fr/pasteur-00217549

S. Absalon, L. Kohl, C. Branche, T. Blisnick, G. Toutirais et al., Basal Body Positioning Is Controlled by Flagellum Formation in Trypanosoma brucei, PLoS ONE, vol.129, issue.24, p.437, 2007.
DOI : 10.1371/journal.pone.0000437.s006

URL : https://hal.archives-ouvertes.fr/pasteur-00169134

C. Adhiambo, T. Blisnick, G. Toutirais, E. Delannoy, and P. Bastin, A novel function for the atypical small G protein Rab-like 5 in the assembly of the trypanosome flagellum, Journal of Cell Science, vol.122, issue.6, pp.834-841, 2009.
DOI : 10.1242/jcs.040444

C. Adhiambo, J. Forney, D. Asai, and J. Lebowitz, The two cytoplasmic dynein-2 isoforms in Leishmania mexicana perform separate functions, Molecular and Biochemical Parasitology, vol.143, issue.2, pp.216-225, 2005.
DOI : 10.1016/j.molbiopara.2005.04.017

N. Ahmed, C. Gao, B. Lucker, D. Cole, and D. Mitchell, ODA16 aids axonemal outer row dynein assembly through an interaction with the intraflagellar transport machinery, The Journal of Cell Biology, vol.109, issue.2, pp.313-322, 2008.
DOI : 10.1146/annurev.physiol.69.040705.141301

H. Arts, E. Bongers, D. Mans, S. Van-beersum, M. Oud et al., C14ORF179 encoding IFT43 is mutated in Sensenbrenner syndrome, Journal of Medical Genetics, vol.48, issue.6, pp.390-395, 2011.
DOI : 10.1136/jmg.2011.088864

URL : https://hal.archives-ouvertes.fr/hal-00613258

M. Porter, R. Bower, J. Knott, P. Byrd, and W. Dentler, Cytoplasmic Dynein Heavy Chain 1b Is Required for Flagellar Assembly in Chlamydomonas, Molecular Biology of the Cell, vol.10, issue.3, pp.693-712, 1999.
DOI : 10.1091/mbc.10.3.693

L. Pradel, M. Bonhivers, N. Landrein, and D. Robinson, NIMA-related kinase TbNRKC is involved in basal body separation in Trypanosoma brucei, Journal of Cell Science, vol.119, issue.9, pp.1852-1863, 2006.
DOI : 10.1242/jcs.02900

URL : https://hal.archives-ouvertes.fr/hal-00215921

H. Qin, J. Rosenbaum, and M. Barr, An autosomal recessive polycystic kidney disease gene homolog is involved in intraflagellar transport in C. elegans ciliated sensory neurons, Current Biology, vol.11, issue.6, pp.457-461, 2001.
DOI : 10.1016/S0960-9822(01)00122-1

K. Ralston, Z. Kabututu, J. Melehani, M. Oberholzer, and K. Hill, Flagellum: Moving Parasites in New Directions, Annual Review of Microbiology, vol.63, issue.1, pp.335-362, 2009.
DOI : 10.1146/annurev.micro.091208.073353

S. Redmond, J. Vadivelu, and M. Field, RNAit: an automated web-based tool for the selection of RNAi targets in Trypanosoma brucei, Molecular and Biochemical Parasitology, vol.128, issue.1, pp.115-118, 2003.
DOI : 10.1016/S0166-6851(03)00045-8

P. Rompolas, L. Pedersen, R. Patel-king, and S. King, Chlamydomonas FAP133 is a dynein intermediate chain associated with the retrograde intraflagellar transport motor, Journal of Cell Science, vol.120, issue.20, pp.3653-3665, 2007.
DOI : 10.1242/jcs.012773

J. Rosenbaum and G. Witman, Intraflagellar transport, Nature Reviews Molecular Cell Biology, vol.418, issue.11, pp.813-825, 2002.
DOI : 10.1038/nrm952

M. Sakato and S. King, Design and regulation of the AAA+ microtubule motor dynein, Journal of Structural Biology, vol.146, issue.1-2, pp.58-71, 2004.
DOI : 10.1016/j.jsb.2003.09.026

J. Schafer, C. Haycraft, J. Thomas, B. Yoder, and P. Swoboda, XBX-1 Encodes a Dynein Light Intermediate Chain Required for Retrograde Intraflagellar Transport and Cilia Assembly in Caenorhabditis elegans, Molecular Biology of the Cell, vol.14, issue.5, pp.2057-2070, 2003.
DOI : 10.1091/mbc.E02-10-0677

G. Schiavo, L. Greensmith, M. Hafezparast, and E. Fisher, Cytoplasmic dynein heavy chain: the servant of many masters, Trends in Neurosciences, vol.36, issue.11, pp.641-651, 2013.
DOI : 10.1016/j.tins.2013.08.001

M. Schmidts, J. Vodopiutz, S. Christou-savina, C. Cortes, A. Mcinerney-leo et al., Mutations in the Gene Encoding IFT Dynein Complex Component WDR34 Cause Jeune Asphyxiating Thoracic Dystrophy, The American Journal of Human Genetics, vol.93, issue.5, pp.932-944, 2013.
DOI : 10.1016/j.ajhg.2013.10.003

J. Scholey, Kinesin-2: A Family of Heterotrimeric and Homodimeric Motors with Diverse Intracellular Transport Functions, Annual Review of Cell and Developmental Biology, vol.29, issue.1, pp.443-469, 2013.
DOI : 10.1146/annurev-cellbio-101512-122335

D. Smith and K. Johnson, Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase, Gene, vol.67, issue.1, pp.31-40, 1988.
DOI : 10.1016/0378-1119(88)90005-4

I. Subota, D. Julkowska, L. Vincensini, N. Reeg, J. Buisson et al., Proteomic Analysis of Intact Flagella of Procyclic Trypanosoma brucei Cells Identifies Novel Flagellar Proteins with Unique Sub-localization and Dynamics, Molecular & Cellular Proteomics, vol.13, issue.7, pp.1769-1786, 2014.
DOI : 10.1074/mcp.M113.033357

URL : https://hal.archives-ouvertes.fr/pasteur-01301216

I. Subota, B. Rotureau, T. Blisnick, S. Ngwabyt, M. Durand-dubief et al., ALBA proteins are stage regulated during trypanosome development in the tsetse fly and participate in differentiation, Molecular Biology of the Cell, vol.22, issue.22, pp.4205-4219, 2011.
DOI : 10.1091/mbc.E11-06-0511

URL : https://hal.archives-ouvertes.fr/pasteur-01371322

R. Vale, The Molecular Motor Toolbox for Intracellular Transport, Cell, vol.112, issue.4, pp.467-480, 2003.
DOI : 10.1016/S0092-8674(03)00111-9

J. Walczak-sztulpa, J. Eggenschwiler, D. Osborn, D. Brown, E. F. Klingenberg et al., Cranioectodermal Dysplasia, Sensenbrenner Syndrome, Is a Ciliopathy Caused by Mutations in the IFT122 Gene, The American Journal of Human Genetics, vol.86, issue.6, pp.949-956, 2010.
DOI : 10.1016/j.ajhg.2010.04.012

Z. Wang, Z. Fan, S. Williamson, and H. Qin, Intraflagellar Transport (IFT) Protein IFT25 Is a Phosphoprotein Component of IFT Complex B and Physically Interacts with IFT27 in Chlamydomonas, PLoS ONE, vol.176, issue.5, p.5384, 2009.
DOI : 10.1371/journal.pone.0005384.s001

Z. Wang, J. Morris, M. Drew, and P. Englund, Inhibition of Trypanosoma brucei Gene Expression by RNA Interference Using an Integratable Vector with Opposing T7 Promoters, Journal of Biological Chemistry, vol.275, issue.51, pp.40174-40179, 2000.
DOI : 10.1074/jbc.M008405200

C. Williams, C. Li, K. Kida, P. Inglis, S. Mohan et al., MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis, The Journal of Cell Biology, vol.11, issue.6, pp.1023-1041, 2011.
DOI : 10.1016/j.tig.2010.01.006

E. Wirtz, S. Leal, C. Ochatt, and G. Cross, A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei, Molecular and Biochemical Parasitology, vol.99, issue.1, pp.89-101, 1999.
DOI : 10.1016/S0166-6851(99)00002-X

K. Wren, J. Craft, D. Tritschler, A. Schauer, D. Patel et al., A Differential Cargo-Loading Model of Ciliary Length Regulation by IFT, Current Biology, vol.23, issue.24, pp.2463-2471, 2013.
DOI : 10.1016/j.cub.2013.10.044

L. Hao, E. Efimenko, P. Swoboda, and J. Scholey, The Retrograde IFT Machinery of C. elegans Cilia: Two IFT Dynein Complexes?, PLoS ONE, vol.17, issue.6, 2011.
DOI : 10.1371/journal.pone.0020995.s002

E. Hom, G. Witman, E. Harris, S. Dutcher, R. Kamiya et al., A unified taxonomy for ciliary dyneins, Cytoskeleton, vol.190, issue.10, pp.555-565, 2011.
DOI : 10.1002/cm.20533

Y. Hou, G. Pazour, and G. Witman, A Dynein Light Intermediate Chain, D1bLIC, Is Required for Retrograde Intraflagellar Transport, Molecular Biology of the Cell, vol.15, issue.10, pp.4382-4394, 2004.
DOI : 10.1091/mbc.E04-05-0377

C. Huber, S. Wu, A. Kim, S. Sigaudy, A. Sarukhanov et al., WDR34 Mutations that Cause Short-Rib Polydactyly Syndrome Type III/Severe Asphyxiating Thoracic Dysplasia Reveal a Role for the NF-??B Pathway in Cilia, The American Journal of Human Genetics, vol.93, issue.5, pp.926-931, 2013.
DOI : 10.1016/j.ajhg.2013.10.007

C. Iomini, L. Li, J. Esparza, and S. Dutcher, Retrograde Intraflagellar Transport Mutants Identify Complex A Proteins With Multiple Genetic Interactions in Chlamydomonas reinhardtii, Genetics, vol.183, issue.3, pp.885-896, 2009.
DOI : 10.1534/genetics.109.101915

A. Jackson, M. Quail, and M. Berriman, Insights into the genome sequence of a free-living Kinetoplastid: Bodo saltans (Kinetoplastida: Euglenozoa), BMC Genomics, vol.9, issue.1, p.594, 2008.
DOI : 10.1186/1471-2164-9-594

G. Jekely and D. Arendt, Evolution of intraflagellar transport from coated vesicles and autogenous origin of the eukaryotic ciliumBioEssays, pp.191-198, 2006.

L. Kohl and P. Bastin, The Flagellum of Trypanosomes, Int Rev Cytol, vol.244, pp.227-285, 2005.
DOI : 10.1016/S0074-7696(05)44006-1

URL : https://hal.archives-ouvertes.fr/hal-00109408

L. Kohl, D. Robinson, and P. Bastin, Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes, The EMBO Journal, vol.22, issue.20, pp.5336-5346, 2003.
DOI : 10.1093/emboj/cdg518

URL : https://hal.archives-ouvertes.fr/hal-00108210

L. Kohl, T. Sherwin, and K. Gull, Assembly of the Paraflagellar Rod and the Flagellum Attachment Zone Complex During the Trypanosoma brucei Cell Cycle, The Journal of Eukaryotic Microbiology, vol.95, issue.2, pp.105-109, 1999.
DOI : 10.1083/jcb.104.3.439

K. Kozminski, K. Johnson, P. Forscher, and J. Rosenbaum, A motility in the eukaryotic flagellum unrelated to flagellar beating., Proceedings of the National Academy of Sciences, vol.90, issue.12, pp.5519-5523, 1993.
DOI : 10.1073/pnas.90.12.5519

B. Krock, I. Mills-henry, and B. Perkins, Retrograde Intraflagellar Transport by Cytoplasmic Dynein-2 Is Required for Outer Segment Extension in Vertebrate Photoreceptors but Not Arrestin Translocation, Investigative Opthalmology & Visual Science, vol.50, issue.11, pp.5463-5471, 2009.
DOI : 10.1167/iovs.09-3828

B. Morga and P. Bastin, Getting to the heart of intraflagellar transport using Trypanosoma and Chlamydomonas models: the strength is in their differences, Cilia, vol.2, issue.1, p.16, 2013.
DOI : 10.1111/j.1462-5822.2010.01566.x

URL : https://hal.archives-ouvertes.fr/pasteur-00911797

S. Mukhopadhyay, X. Wen, B. Chih, C. Nelson, W. Lane et al., TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia, Genes & Development, vol.24, issue.19, pp.2180-2193, 2010.
DOI : 10.1101/gad.1966210

K. Nikulina, R. Patel-king, S. Takebe, K. Pfister, and S. King, The roadblock light chains are ubiquitous components of cytoplasmic dynein that form homo- and heterodimers, Cell Motility and the Cytoskeleton, vol.275, issue.4, pp.233-245, 2004.
DOI : 10.1002/cm.10172

H. Omran, D. Kobayashi, H. Olbrich, T. Tsukahara, N. Loges et al., Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins, Nature, vol.7, issue.7222, pp.611-616, 2008.
DOI : 10.1038/nature07471

R. Patel-king, R. Gilberti, E. Hom, and S. King, WD60/FAP163 is a dynein intermediate chain required for retrograde intraflagellar transport in cilia, Molecular Biology of the Cell, vol.24, issue.17, pp.2668-2677, 2013.
DOI : 10.1091/mbc.E13-05-0266

G. Pazour, B. Dickert, and G. Witman, The DHC1b (DHC2) Isoform of Cytoplasmic Dynein Is Required for Flagellar Assembly, The Journal of Cell Biology, vol.107, issue.3, pp.473-481, 1999.
DOI : 10.1083/jcb.137.7.1537

G. Pazour, C. Wilkerson, and G. Witman, A Dynein Light Chain Is Essential for the Retrograde Particle Movement of Intraflagellar Transport (IFT), The Journal of Cell Biology, vol.108, issue.4, 1998.
DOI : 10.1073/pnas.91.6.2100

L. Pedersen, S. Geimer, and J. Rosenbaum, Dissecting the Molecular Mechanisms of Intraflagellar Transport in Chlamydomonas, Current Biology, vol.16, issue.5, pp.450-459, 2006.
DOI : 10.1016/j.cub.2006.02.020

L. Perkins, E. Hedgecock, J. Thomson, and J. Culotti, Mutant sensory cilia in the nematode Caenorhabditis elegans, Developmental Biology, vol.117, issue.2, pp.456-487, 1986.
DOI : 10.1016/0012-1606(86)90314-3

I. Perrault, S. Saunier, S. Hanein, E. Filhol, A. Bizet et al., Mainzer-Saldino Syndrome Is a Ciliopathy Caused by IFT140 Mutations, The American Journal of Human Genetics, vol.90, issue.5, pp.864-870, 2012.
DOI : 10.1016/j.ajhg.2012.03.006

URL : https://hal.archives-ouvertes.fr/inserm-00752958