M. N. Thank and I. A. Pasteur-for-support, thanks Unilever and the European Research Commission (Starting Grant ERC-2013- StG 336159 MIXTURE) for funding, M.N. thanks the Investissement d'Avenir Bioinformatics Program (Grant Bip:Bip) and the European Research Commission (Advanced Grant ERC-2011-StG 294809 BayCellS) for funding. Conflict of Interest: none declared

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