Molecular Characterization of Streptococcus agalactiae Isolates Harboring Small erm(T)-Carrying Plasmids

Fabrice Compain (1) , Constantin Hays (2, 1) , Gérald Touak (1, 2) , Nicolas Dmytruk (1, 2) , Patrick Trieu-Cuot (3) , Caroline Joubrel (1, 2) , Claire Poyart (1, 3, 2)

1 Centre national de Référence des Streptocoques (CNR)
2 DHU Risques Et Grossesse
3 Biologie des Bactéries pathogènes à Gram-positif

Among 1,827 group B Streptococcus (GBS) strains collected between 2006 and 2013 by the French National Reference Center for Streptococci, 490 (26.8%) strains were erythromycin resistant. The erm(T) resistance gene was found in six strains belonging to capsular polysaccharides Ia, III, and V and was carried by the same mobilizable plasmid, which could be efficiently transferred by mobilization to GBS and Enterococcus faecalis recipients, thus promoting a broad dissemination of erm(T).

Domaines: Bactériologie

Fabrice Compain, Constantin Hays, Gérald Touak, Nicolas Dmytruk, Patrick Trieu-Cuot, et al.. Molecular Characterization of Streptococcus agalactiae Isolates Harboring Small erm(T)-Carrying Plasmids. Antimicrobial Agents and Chemotherapy, 2014, 58 (11), pp.6928-6930. ⟨10.1128/aac.03855-14⟩. ⟨pasteur-01299771⟩