Virus de l???h??patite C, m??decine/sciences, vol.29, issue.11, pp.998-1003, 2013. ,
DOI : 10.1051/medsci/20132911016
Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430, Nature, vol.47, issue.7496, pp.402-407, 2014. ,
DOI : 10.1038/nature13027
Antivirals and resistance: influenza virus, Current Opinion in Virology, vol.1, issue.6, pp.563-73, 2011. ,
DOI : 10.1016/j.coviro.2011.09.002
Systematic Approaches towards the Development of Host-Directed Antiviral Therapeutics, International Journal of Molecular Sciences, vol.12, issue.12, pp.4027-52, 2011. ,
DOI : 10.3390/ijms12064027
Regulators of innate immunity as novel targets for panviral therapeutics, Current Opinion in Virology, vol.2, issue.5, pp.622-630, 2012. ,
DOI : 10.1016/j.coviro.2012.08.009
High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses, Journal of Visualized Experiments, vol.87, issue.87, p.51222, 2014. ,
DOI : 10.3791/51222
URL : https://hal.archives-ouvertes.fr/pasteur-01113538
Interferon-inducible effector mechanisms in cell-autonomous immunity, Nature Reviews Immunology, vol.105, issue.5, pp.367-82, 2012. ,
DOI : 10.1038/nri3210
Pattern Recognition Receptors and the Innate Immune Response to Viral Infection, Viruses, vol.3, issue.6, pp.920-960, 2011. ,
DOI : 10.3390/v3060920
Inhibition of Pyrimidine Biosynthesis Pathway Suppresses Viral Growth through Innate Immunity, PLoS Pathogens, vol.8, issue.10, p.1003678, 2013. ,
DOI : 10.1371/journal.ppat.1003678.s014
URL : https://hal.archives-ouvertes.fr/pasteur-01113535
Isoflavone Agonists of IRF-3 Dependent Signaling Have Antiviral Activity against RNA Viruses, Journal of Virology, vol.86, issue.13, pp.7334-7378, 2012. ,
DOI : 10.1128/JVI.06867-11
Identification of Small Molecule Activators of the Janus Kinase/Signal Transducer and Activator of Transcription Pathway Using a Cell-Based Screen, Biological & Pharmaceutical Bulletin, vol.35, issue.1, pp.65-71, 2012. ,
DOI : 10.1248/bpb.35.65
High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery, PLoS ONE, vol.3, issue.5, p.36594, 2012. ,
DOI : 10.1371/journal.pone.0036594.s002
Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV), Proceedings of the National Academy of Sciences, vol.108, issue.17, pp.6739-6783, 2011. ,
DOI : 10.1073/pnas.1017142108
Inhibition of Dengue Virus through Suppression of Host Pyrimidine Biosynthesis, Journal of Virology, vol.85, issue.13, pp.6548-56, 2011. ,
DOI : 10.1128/JVI.02510-10
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis, Proceedings of the National Academy of Sciences, vol.108, issue.14, pp.5777-82, 2011. ,
DOI : 10.1073/pnas.1101143108
D282, a Non-Nucleoside Inhibitor of Influenza Virus Infection that Interferes with De Novo Pyrimidine Biosynthesis, Antiviral Chemistry and Chemotherapy, vol.22, issue.6, pp.263-72, 2012. ,
DOI : 10.3851/IMP2105
On Dihydroorotate Dehydrogenases and Their Inhibitors and Uses, Journal of Medicinal Chemistry, vol.56, issue.8, pp.3148-67, 2013. ,
DOI : 10.1021/jm301848w
URL : https://hal.archives-ouvertes.fr/pasteur-00819070
Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents, Structure, vol.8, issue.1, pp.25-33, 2000. ,
DOI : 10.1016/S0969-2126(00)00077-0
Inhibition of Arenavirus by A3, a Pyrimidine Biosynthesis Inhibitor, Journal of Virology, vol.88, issue.2, pp.878-89, 2014. ,
DOI : 10.1128/JVI.02275-13
Assessment of drug candidates for broad-spectrum antiviral therapy targeting cellular pyrimidine biosynthesis, Antiviral Research, vol.100, issue.3, pp.640-648, 2013. ,
DOI : 10.1016/j.antiviral.2013.10.003
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays, Journal of Biomolecular Screening, vol.4, issue.2, pp.67-73, 1999. ,
DOI : 10.1177/108705719900400206
Intervention strategies for emerging viruses: use of antivirals, Current Opinion in Virology, vol.3, issue.2, pp.217-241, 2013. ,
DOI : 10.1016/j.coviro.2013.03.001
La rougeole en France, m??decine/sciences, vol.28, issue.11, pp.1003-1010, 2012. ,
DOI : 10.1051/medsci/20122811023
Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis, The Lancet, vol.375, issue.9725, pp.1545-55, 2010. ,
DOI : 10.1016/S0140-6736(10)60206-1
A decade after SARS: strategies for controlling emerging coronaviruses, Nature Reviews Microbiology, vol.84, issue.12, pp.836-884, 2013. ,
DOI : 10.1038/nrmicro3143
Towards an HIV cure: a global scientific strategy, Nat Rev Immunol, vol.12, pp.607-621, 2012. ,
Advances in newly developing therapy for chronic hepatitis C virus infection, Frontiers of Medicine, vol.60, issue.3, pp.166-74, 2014. ,
DOI : 10.1007/s11684-014-0334-2