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Journal articles
Two-component systems and toxinogenesis regulation in Clostridium botulinum
Abstract : Botulinum neurotoxins (BoNTs) are the most potent toxins ever known. BoNTs associate with non-toxic proteins to form complexes of various sizes. Toxin production is highly regulated through complex networks of regulatory systems involving an alternative sigma factor, BotR, and at least 6 two-component systems (TCSs). TCSs allow bacteria to sense environmental changes and to respond to various stimuli by regulating the expression of specific genes at a transcriptional level. This review aims to highlight the role of TCSs as a central point in the regulation of toxin production in C. botulinum.
Cited literature [2 references]
https://hal-pasteur.archives-ouvertes.fr/pasteur-01115185
Contributor : Christine David <>
Submitted on : Tuesday, February 10, 2015 - 4:07:47 PM
Last modification on : Monday, January 13, 2020 - 5:08:05 PM
Long-term archiving on: : Monday, May 11, 2015 - 10:45:31 AM
Contributor : Christine David <>
Submitted on : Tuesday, February 10, 2015 - 4:07:47 PM
Last modification on : Monday, January 13, 2020 - 5:08:05 PM
Long-term archiving on: : Monday, May 11, 2015 - 10:45:31 AM
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