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Salmonella enterica Serotype Typhi with nonclassical quinolone resistance phenotype.

Abstract : We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.
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Marie Accou-Demartin, Valérie Gaborieau, Yajun Song, Philippe Roumagnac, Bruno Marchou, et al.. Salmonella enterica Serotype Typhi with nonclassical quinolone resistance phenotype.. Emerging Infectious Diseases, Centers for Disease Control and Prevention, 2011, 17 (6), pp.1091-4. ⟨10.3201/eid1706.101242⟩. ⟨pasteur-01115158⟩

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