M. Spillantini, M. Schmidt, V. Lee, J. Trojanowski, R. Jakes et al., Alpha-synuclein in Lewy bodies, Nature, vol.388, issue.6645, pp.839-840, 1997.
DOI : 10.1038/42166

K. Wakabayashi, M. Yoshimoto, S. Tsuji, and H. Takahashi, Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy, Neurosci Lett, vol.249, pp.2-3180, 1998.

M. Spillantini, R. Crowther, R. Jakes, N. Cairns, P. Lantos et al., Filamentous ??-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies, Neuroscience Letters, vol.251, issue.3, pp.205-208, 1998.
DOI : 10.1016/S0304-3940(98)00504-7

P. Tu, J. Galvin, M. Baba, B. Giasson, T. Tomita et al., Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein, Ann Neurol, issue.3, pp.44415-422, 1998.

V. Uversky, J. Li, and A. Fink, Evidence for a Partially Folded Intermediate in alpha -Synuclein Fibril Formation, Journal of Biological Chemistry, vol.276, issue.14, pp.27610737-10744, 2001.
DOI : 10.1074/jbc.M010907200

J. Jarrett, P. Lansbury, and . Jr, Seeding ???one-dimensional crystallization??? of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?, Cell, vol.73, issue.6, pp.1055-1058, 1993.
DOI : 10.1016/0092-8674(93)90635-4

H. Baker, R. Ridley, L. Duchen, T. Crow, and C. Bruton, Evidence for the experimental transmission of cerebral beta-amyloidosis to primates, Int J Exp Pathol, vol.74, issue.5, pp.441-454, 1993.

M. Kane, W. Lipinski, M. Callahan, F. Bian, R. Durham et al., Evidence for seeding of beta -amyloid by intracerebral infusion of Alzheimer brain extracts in beta -amyloid precursor protein-transgenic mice, pp.203606-3611, 2000.

M. Meyer-luehmann, J. Coomaraswamy, T. Bolmont, S. Kaeser, C. Schaefer et al., Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host, Science, issue.5794, pp.3131781-1784, 2006.

F. Langer, Y. Eisele, S. Fritschi, M. Staufenbiel, L. Walker et al., Soluble Abeta seeds are potent inducers of cerebral beta-amyloid deposition, J Neurosci, issue.41, pp.3114488-14495, 2011.

M. Goedert, M. Spillantini, D. Tredici, K. Braak, and H. , 100 years of Lewy pathology, Nature Reviews Neurology, vol.21, issue.1, pp.13-24
DOI : 10.1038/nrneurol.2012.242

S. Dearmond and S. Prusiner, Etiology and pathogenesis of prion diseases, Am J Pathol, vol.146, issue.4, pp.785-811, 1995.

J. Silveira, G. Raymond, A. Hughson, R. Race, V. Sim et al., The most infectious prion protein particles, Nature, vol.437, issue.7056, pp.437257-261, 2005.
DOI : 10.1038/nature03989

M. Sandberg, H. Doujaily, B. Sharps, A. Clarke, and J. Collinge, Prion propagation and toxicity in vivo occur in two distinct mechanistic phases, Nature, vol.21, issue.7335, pp.470540-542, 2011.
DOI : 10.1038/nature09768

L. Volpicelli-daley, K. Luk, T. Patel, S. Tanik, D. Riddle et al., Exogenous ??-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death, Neuron, vol.72, issue.1, pp.57-71, 2011.
DOI : 10.1016/j.neuron.2011.08.033

K. Luk, V. Kehm, J. Carroll, B. Zhang, O. Brien et al., Pathological alpha-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice, Science, vol.2012, issue.6109, pp.338949-953

M. Masuda-suzukake, T. Nonaka, M. Hosokawa, T. Oikawa, T. Arai et al., Prion-like spreading of pathological alphasynuclein in brain, Brain, vol.2013, issue.136, pp.1128-1138

L. Bousset, L. Pieri, . Ruiz-arlandisg, . Gathj, . Jensenph et al., Structural and functional characterization of two alpha-synuclein strains, Nature Communications, vol.309, p.2575, 2013.
DOI : 10.1007/s000180050067
URL : https://hal.archives-ouvertes.fr/hal-01183047

K. Luk, C. Song, O. Brien, P. Stieber, A. Branch et al., Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells, Proc Natl Acad Sci, issue.47, pp.10620051-20056, 2009.

G. Legname, I. Baskakov, H. Nguyen, D. Riesner, F. Cohen et al., Synthetic Mammalian Prions, Science, vol.305, issue.5684, pp.305673-676, 2004.
DOI : 10.1126/science.1100195

B. Caughey and P. Lansbury, : Separating the Responsible Protein Aggregates from The Innocent Bystanders, Annual Review of Neuroscience, vol.26, issue.1, pp.267-298, 2003.
DOI : 10.1146/annurev.neuro.26.010302.081142

B. Winner, R. Jappelli, S. Maji, P. Desplats, L. Boyer et al., In vivo demonstration that ??-synuclein oligomers are toxic, Proceedings of the National Academy of Sciences, vol.108, issue.10, pp.4194-4199, 2011.
DOI : 10.1073/pnas.1100976108

K. Danzer, D. Haasen, A. Karow, S. Moussaud, M. Habeck et al., KostkaM:Different species of alphasynuclein oligomers induce calcium influx and seeding, pp.9220-9232, 2007.

H. Schell, T. Hasegawa, M. Neumann, and P. Kahle, Nuclear and neuritic distribution of serine-129 phosphorylated ??-synuclein in transgenic mice, Neuroscience, vol.160, issue.4, pp.796-804, 2009.
DOI : 10.1016/j.neuroscience.2009.03.002

M. Wakamatsu, A. Ishii, Y. Ukai, J. Sakagami, S. Iwata et al., Accumulation of phosphorylated alpha-synuclein in dopaminergic neurons of transgenic mice that express human alpha-synuclein

A. Sacino, M. Thomas, C. Ceballos-diaz, P. Cruz, A. Rosario et al., Conformational templating of ??-synuclein aggregates in neuronal-glial cultures, Molecular Neurodegeneration, vol.8, issue.1, p.17, 2013.
DOI : 10.1002/(SICI)1097-4547(20000215)59:4<528::AID-JNR8>3.0.CO;2-0

P. Bosque and S. Prusiner, Cultured Cell Sublines Highly Susceptible to Prion Infection, Journal of Virology, vol.74, issue.9, pp.4377-4386, 2000.
DOI : 10.1128/JVI.74.9.4377-4386.2000

P. Mellon, J. Windle, P. Goldsmith, C. Padula, J. Roberts et al., Immortalization of hypothalamic GnRH by genetically targeted tumorigenesis, Neuron, vol.5, issue.1, pp.1-10, 1990.
DOI : 10.1016/0896-6273(90)90028-E

J. Biedler, L. Helson, and B. Spengler, Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture, Cancer Res, vol.33, issue.11, pp.2643-2652, 1973.

C. Huang, G. Ren, H. Zhou, and C. Wang, A new method for purification of recombinant human ??-synuclein in Escherichia coli, Protein Expression and Purification, vol.42, issue.1, pp.173-177, 2005.
DOI : 10.1016/j.pep.2005.02.014

D. Latawiec, F. Herrera, A. Bek, V. Losasso, M. Candotti et al., Modulation of Alpha-Synuclein Aggregation by Dopamine Analogs, PLoS ONE, vol.26, issue.5, p.9234, 2010.
DOI : 10.1371/journal.pone.0009234.s007