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Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice

Nicolas Tchitchek 1 Amie Eisfeld 2 Jennifer Tisoncik-Go 1 Laurence Josset 1 Lisa Gralinski 3 Christophe Bécavin 4 Susan Tilton 5 Bobbie-Jo Webb-Robertson 5 Martin Ferris 3 Allison Totura 3 Chengjun Li 2 Gabriele Neumann 2 Thomas Metz 5 Richard Smith 5 Katrina Waters 5 Ralph Baric 3 yoshihiro Kawaoka 2 Michael Katze 1, 6, * 
* Corresponding author
1 Department of Microbiology
2 School of Veterinary Medicine, Department of Pathobiological Sciences
3 Department of Microbiology and Immunology, School of Medicine
4 UIBC - Interactions Bactéries-Cellules
5 Biological Sciences Division
6 Washington National Primate Research Center [Seattle]
Abstract : Influenza infection causes respiratory disease that can lead to death. The complex interplay between virus-encoded and host-specific pathogenicity regulators - and the relative contributions of each toward viral pathogenicity - is not well-understood
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https://hal-pasteur.archives-ouvertes.fr/pasteur-00850969
Contributor : Ed. BMC Connect in order to contact the contributor
Submitted on : Friday, August 9, 2013 - 9:09:42 PM
Last modification on : Thursday, May 19, 2022 - 4:48:04 PM

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Nicolas Tchitchek, Amie Eisfeld, Jennifer Tisoncik-Go, Laurence Josset, Lisa Gralinski, et al.. Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice. BMC Systems Biology, BioMed Central, 2013, 7 (1), pp.69. ⟨10.1186/1752-0509-7-69⟩. ⟨pasteur-00850969⟩

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