Acquired Immunity to Malaria, Clinical Microbiology Reviews, vol.22, issue.1, pp.13-36, 2009. ,
DOI : 10.1128/CMR.00025-08
The silent path to thousands of merozoites: the Plasmodium liver stage, Nature Reviews Microbiology, vol.98, issue.11, pp.849-856, 2006. ,
DOI : 10.1038/nrmicro1529
Plasmodium pre-erythrocytic stages: what???s new?, Trends in Parasitology, vol.24, issue.12, pp.564-569, 2008. ,
DOI : 10.1016/j.pt.2008.08.009
The malaria merozoite, forty years on, Parasitology, vol.67, issue.12, pp.1435-1444, 2009. ,
DOI : 10.1084/jem.149.1.172
Human immunization with attenuated sporozoites, Bull World Health Organ, vol.68, pp.13-16, 1990. ,
Specificity of Protective Immunity produced by X-irradiated Plasmodium berghei Sporozoites, Nature, vol.212, issue.5192, pp.488-489, 1969. ,
DOI : 10.1016/0014-4894(67)90084-7
Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8+ T Cell Immunity, Science, vol.334, issue.6055, pp.475-480, 2011. ,
DOI : 10.1126/science.1211548
Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine, Proceedings of the National Academy of Sciences, vol.95, issue.13, pp.7648-7653, 1998. ,
DOI : 10.1073/pnas.95.13.7648
Adenovirus-5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part B: Safety, Immunogenicity and Protective Efficacy of the CSP Component, PLoS ONE, vol.6, issue.10, p.25868, 2011. ,
DOI : 10.1371/journal.pone.0025868.s005
Phase Ia Clinical Evaluation of the Safety and Immunogenicity of the Plasmodium falciparum Blood-Stage Antigen AMA1 in ChAd63 and MVA Vaccine Vectors, PLoS ONE, vol.187, issue.2, p.31208, 2012. ,
DOI : 10.1371/journal.pone.0031208.s017
A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray, Proceedings of the National Academy of Sciences, vol.107, issue.15, pp.6958-6963, 2010. ,
DOI : 10.1073/pnas.1001323107
Vaccines against malaria, Philosophical Transactions of the Royal Society B: Biological Sciences, vol.6, issue.1, pp.2806-2814, 2011. ,
DOI : 10.4161/hv.6.1.9931
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146776
Malaria Candidate Vaccine When Integrated in the Expanded Program of Immunization, The Journal of Infectious Diseases, vol.202, issue.7, pp.1076-1087, 2011. ,
DOI : 10.1086/656190
Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS,S/AS01 malaria vaccine in African children, Malaria Journal, vol.10, issue.1, p.222, 2011. ,
DOI : 10.1186/1475-2875-8-116
Development of the malaria parasite in the skin of the mammalian host, Proceedings of the National Academy of Sciences, vol.107, issue.43, pp.18640-18645, 2010. ,
DOI : 10.1073/pnas.1009346107
Host Cell Traversal Is Important for Progression of the Malaria Parasite through the Dermis to the Liver, Cell Host & Microbe, vol.3, issue.2, pp.88-96, 2008. ,
DOI : 10.1016/j.chom.2007.12.007
Release of Hepatic Plasmodium yoelii Merozoites into the Pulmonary Microvasculature, PLoS Pathogens, vol.153, issue.11, p.171, 2007. ,
DOI : 10.1371/journal.ppat.0030171.sv010
Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo, PLoS Pathogens, vol.80, issue.3, 2011. ,
DOI : 10.1371/journal.ppat.1001318.s005
Protracted Protection to Plasmodium berghei Malaria Is Linked to Functionally and Phenotypically Heterogeneous Liver Memory CD8+ T Cells, The Journal of Immunology, vol.171, issue.4, 2003. ,
DOI : 10.4049/jimmunol.171.4.2024
Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria, Proceedings of the National Academy of Sciences, vol.105, issue.37, pp.14017-14022, 2008. ,
DOI : 10.1073/pnas.0805452105
CD8+ T Effector Memory Cells Protect against Liver-Stage Malaria, The Journal of Immunology, vol.187, issue.3, pp.1347-1357, 2011. ,
DOI : 10.4049/jimmunol.1100302
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568294
Long Term Protection after Immunization with P. berghei Sporozoites Correlates with Sustained IFN?? Responses of Hepatic CD8+ Memory T Cells, PLoS ONE, vol.3, issue.5, p.36508, 2012. ,
DOI : 10.1371/journal.pone.0036508.t002
Skin-Derived Dendritic Cells Induce Potent CD8+ T Cell Immunity in Recombinant Lentivector-Mediated Genetic Immunization, Immunity, vol.24, issue.5, pp.643-656, 2006. ,
DOI : 10.1016/j.immuni.2006.03.014
Immunization with a Lentiviral Vector Stimulates both CD4 and CD8 T Cell Responses to an Ovalbumin Transgene, Molecular Therapy, vol.13, issue.2, pp.310-319, 2006. ,
DOI : 10.1016/j.ymthe.2005.08.025
Lentiviral Vectors Encoding HIV-1 Polyepitopes Induce Broad CTL Responses In Vivo, Molecular Therapy, vol.15, issue.6, pp.1203-1210, 2007. ,
DOI : 10.1038/sj.mt.6300135
URL : https://hal.archives-ouvertes.fr/hal-00167663
A single immunization with a minute dose of a lentiviral vector-based vaccine is highly effective at eliciting protective humoral immunity against West Nile virus, The Journal of Gene Medicine, vol.302, issue.3, pp.265-274, 2006. ,
DOI : 10.1002/jgm.837
Processing of Tumor-Associated Antigen by the Proteasomes of Dendritic Cells Controls In vivo T-Cell Responses, Cancer Research, vol.66, issue.10, pp.5461-5468, 2006. ,
DOI : 10.1158/0008-5472.CAN-05-4310
Lentiviral Vector-Based Prime/Boost Vaccination against AIDS: Pilot Study Shows Protection against Simian Immunodeficiency Virus SIVmac251 Challenge in Macaques, Journal of Virology, vol.83, issue.21, pp.10963-10974, 2009. ,
DOI : 10.1128/JVI.01284-09
URL : https://hal.archives-ouvertes.fr/pasteur-00457819
Targeting human telomerase reverse transcriptase with recombinant lentivector is highly effective to stimulate antitumor CD8 T-cell immunity in vivo, Blood, vol.115, issue.15, pp.3025-3032, 2010. ,
DOI : 10.1182/blood-2009-11-253641
URL : https://hal.archives-ouvertes.fr/pasteur-00460451
Tubulovesicular Structures within Vesicular Stomatitis Virus G Protein-Pseudotyped Lentiviral Vector Preparations Carry DNA and Stimulate Antiviral Responses via Toll-Like Receptor 9, Journal of Virology, vol.81, issue.2, pp.539-547, 2007. ,
DOI : 10.1128/JVI.01818-06
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797478
HIV-1 Lentiviral Vector Immunogenicity Is Mediated by Toll-Like Receptor 3 (TLR3) and TLR7, Journal of Virology, vol.84, issue.11, pp.5627-5636, 2010. ,
DOI : 10.1128/JVI.00014-10
HIV-1-Derived Lentiviral Vectors Directly Activate Plasmacytoid Dendritic Cells, Which in Turn Induce the Maturation of Myeloid Dendritic Cells, Human Gene Therapy, vol.22, issue.2, pp.177-188, 2011. ,
DOI : 10.1089/hum.2010.085
In vivo administration of a lentiviral vaccine targets DCs and induces efficient CD8+ T cell responses, Journal of Clinical Investigation, vol.111, issue.11, pp.1673-1681, 2003. ,
DOI : 10.1172/JCI200317098
The Role of Skin-Derived Dendritic Cells in CD8+ T Cell Priming Following Immunization with Lentivectors, The Journal of Immunology, vol.184, issue.9, pp.4889-4897, 2010. ,
DOI : 10.4049/jimmunol.0903062
C h a k r a v e r t yR ,B e n n e t tC L( 2 0 1 1 ) Conventional dendritic cells are required for the activation of helper-dependent CD8 T cell responses to a model antigen after cutaneous vaccination with lentiviral vectors, J Immunol, vol.186, pp.4565-4572 ,
Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration, Nature Biotechnology, vol.12, issue.6, pp.687-696, 2006. ,
DOI : 10.1038/nbt1216
Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1, Journal of Clinical Investigation, vol.118, issue.9, pp.3132-3142, 2008. ,
DOI : 10.1172/JCI35700DS1
The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy, Journal of Clinical Investigation, vol.119, issue.4, 2009. ,
DOI : 10.1172/JCI37630DS1
HIV-derived vectors for therapy and vaccination against HIV, Vaccine, vol.30, issue.15, pp.2499-2509, 2012. ,
DOI : 10.1016/j.vaccine.2012.01.089
Integration-deficient Lentiviral Vectors: A Slow Coming of Age, Molecular Therapy, vol.17, issue.8, pp.1316-1332, 2009. ,
DOI : 10.1038/mt.2009.122
Novel Integrase-Defective Lentiviral Episomal Vectors for Gene Transfer, Human Gene Therapy, vol.15, issue.4, pp.361-372, 2004. ,
DOI : 10.1089/104303404322959515
Effective gene therapy with nonintegrating lentiviral vectors, Nature Medicine, vol.25, issue.3, pp.348-353, 2006. ,
DOI : 10.1038/nm1365
Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo, Proceedings of the National Academy of Sciences, vol.103, issue.47, pp.17684-17689, 2006. ,
DOI : 10.1073/pnas.0606197103
URL : https://hal.archives-ouvertes.fr/hal-00166677
Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk, Hepatology, vol.267, issue.Suppl, pp.1696-1707, 2011. ,
DOI : 10.1002/hep.24230
Protective Antiviral Immunity Conferred by a Nonintegrative Lentiviral Vector-Based Vaccine, PLoS ONE, vol.101, issue.12, p.3973, 2008. ,
DOI : 10.1371/journal.pone.0003973.g005
URL : https://hal.archives-ouvertes.fr/pasteur-00457795
Successful Immunization with a Single Injection of Non-integrating Lentiviral Vector, Molecular Therapy, vol.15, issue.9, pp.1716-1723, 2007. ,
DOI : 10.1038/sj.mt.6300241
Nonintegrating Lentivector Vaccines Stimulate Prolonged T-Cell and Antibody Responses and Are Effective in Tumor Therapy, Journal of Virology, vol.83, issue.7, pp.3094-3103, 2009. ,
DOI : 10.1128/JVI.02519-08
Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice, Journal of Biomedicine and Biotechnology, vol.272, issue.5259, p.534501, 2010. ,
DOI : 10.1371/journal.pone.0007226
Nonintegrating Lentiviral Vectors Can Effectively Deliver Ovalbumin Antigen for Induction of Antitumor Immunity, Human Gene Therapy, vol.20, issue.12, pp.1652-1664, 2009. ,
DOI : 10.1089/hum.2009.012
Vaccines delivered by integration-deficient lentiviral vectors targeting dendritic cells induces strong antigen-specific immunity, Vaccine, vol.28, issue.41, pp.6675-6683, 2010. ,
DOI : 10.1016/j.vaccine.2010.08.012
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956406
Successful therapeutic vaccination with integrase defective lentiviral vector expressing nononcogenic human papillomavirus E7 protein, International Journal of Cancer, vol.56, issue.2 Suppl, 2012. ,
DOI : 10.1002/ijc.27676
From the circumsporozoite protein to the RTS,S/AS candidate vaccine, Human Vaccines, vol.6, issue.1, pp.90-96, 2010. ,
DOI : 10.4161/hv.6.1.9677
Monovalent fragments (Fab) of monoclonal antibodies to a sporozoite surface antigen (Pb44) protect mice against malarial infection, Journal of Experimental Medicine, vol.151, issue.6, pp.1504-1513, 1980. ,
DOI : 10.1084/jem.151.6.1504
The relative contribution of antibodies, CD4+ and CD8+ T cells to sporozoite-induced protection against malaria, Immunology, vol.80, pp.1-5, 1993. ,
The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites, Nature, vol.252, issue.7121, pp.937-940, 2006. ,
DOI : 10.1038/nature05361
Class II-Restricted Protective Immunity Induced by Malaria Sporozoites, Infection and Immunity, vol.76, issue.3, pp.1200-1206, 2008. ,
DOI : 10.1128/IAI.00566-07
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258813
Human immunodeficiency virus type 1 integrase mutants retain in vitro integrase activity yet fail to integrate viral DNA efficiently during infection, J Virol, vol.70, pp.721-728, 1996. ,
Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes, Journal of Experimental Medicine, vol.171, issue.3, pp.763-773, 1990. ,
DOI : 10.1084/jem.171.3.763
A Subdominant CD8+ Cytotoxic T Lymphocyte (CTL) Epitope from the Plasmodium yoelii Circumsporozoite Protein Induces CTLs That Eliminate Infected Hepatocytes from Culture, Infection and Immunity, vol.68, issue.6, pp.3403-3411, 2000. ,
DOI : 10.1128/IAI.68.6.3403-3411.2000
Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen, Proceedings of the National Academy of Sciences, vol.98, issue.20, pp.11491-11496, 2001. ,
DOI : 10.1073/pnas.191380898
Conserved Protective Mechanisms in Radiation and Genetically Attenuated uis3(-) and uis4(-) Plasmodium Sporozoites, PLoS ONE, vol.31, issue.12, p.4480, 2009. ,
DOI : 10.1371/journal.pone.0004480.t001
Extreme CD8 T Cell Requirements for Anti-Malarial Liver-Stage Immunity following Immunization with Radiation Attenuated Sporozoites, PLoS Pathogens, vol.11, issue.4, p.1000998, 2010. ,
DOI : 10.1371/journal.ppat.1000998.s005
Plasmodium-Host Interactions Directly Influence the Threshold of Memory CD8 T Cells Required for Protective Immunity, The Journal of Immunology, vol.186, issue.10, pp.5873-5884, 2011. ,
DOI : 10.4049/jimmunol.1100194
Effector CD8+ T Lymphocytes against Liver Stages of Plasmodium yoelii Do Not Require Gamma Interferon for Antiparasite Activity, Infection and Immunity, vol.76, issue.8, pp.3628-3631, 2008. ,
DOI : 10.1128/IAI.00471-08
Genetically Attenuated Parasite Vaccines Induce Contact-Dependent CD8+ T Cell Killing of Plasmodium yoelii Liver Stage-Infected Hepatocytes, The Journal of Immunology, vol.183, issue.9, pp.5870-5878, 2009. ,
DOI : 10.4049/jimmunol.0900302
Sporozoites, The Journal of Immunology, vol.184, issue.5, pp.2528-2538, 2010. ,
DOI : 10.4049/jimmunol.0903529
Sterile Protection against Malaria Is Independent of Immune Responses to the Circumsporozoite Protein, PLoS ONE, vol.22, issue.12, p.1371, 2007. ,
DOI : 10.1371/journal.pone.0001371.g005
A Role for Immune Responses against Non-CS Components in the Cross-Species Protection Induced by Immunization with Irradiated Malaria Sporozoites, PLoS ONE, vol.20, issue.11, p.7717, 2009. ,
DOI : 10.1371/journal.pone.0007717.s007
Minimal Role for the Circumsporozoite Protein in the Induction of Sterile Immunity by Vaccination with Live Rodent Malaria Sporozoites, Infection and Immunity, vol.78, issue.5, pp.2182-2188, 2010. ,
DOI : 10.1128/IAI.01415-09
Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data, Proceedings of the National Academy of Sciences, vol.100, issue.17, pp.9952-9957, 2003. ,
DOI : 10.1073/pnas.1633254100
Superior Antimalarial Immunity after Vaccination with Late Liver Stage-Arresting Genetically Attenuated Parasites, Cell Host & Microbe, vol.9, issue.6, pp.451-462, 2011. ,
DOI : 10.1016/j.chom.2011.05.008
URL : http://doi.org/10.1016/j.chom.2011.05.008
Efficient induction of protective anti-malaria immunity by recombinant adenovirus, Vaccine, vol.16, issue.19, pp.1812-1817, 1998. ,
DOI : 10.1016/S0264-410X(98)00181-9
Prime-Boost Immunization with Adenoviral and Modified Vaccinia Virus Ankara Vectors Enhances the Durability and Polyfunctionality of Protective Malaria CD8+ T-Cell Responses, Infection and Immunity, vol.78, issue.1, pp.145-153, 2010. ,
DOI : 10.1128/IAI.00740-09
Murine T Cells Potently Restrict Human Immunodeficiency Virus Infection, Journal of Virology, vol.78, issue.22, pp.12537-12547, 2004. ,
DOI : 10.1128/JVI.78.22.12537-12547.2004
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525105
Matrix-Induced Inhibition of Membrane Binding Contributes to Human Immunodeficiency Virus Type 1 Particle Assembly Defects in Murine Cells, Journal of Virology, vol.79, issue.24, pp.15586-15589, 2005. ,
DOI : 10.1128/JVI.79.24.15586-15589.2005
Nuclear Import of the Preintegration Complex Is Blocked upon Infection by Human Immunodeficiency Virus Type 1 in Mouse Cells, Journal of Virology, vol.81, issue.2, pp.677-688, 2007. ,
DOI : 10.1128/JVI.00870-06
Mouse T-cells restrict replication of human immunodeficiency virus at the level of integration, Retrovirology, vol.5, issue.1, p.58, 2008. ,
DOI : 10.1038/385645a0
Efficient transduction of myeloid cells by an HIV-1-derived lentiviral vector that packages the Vpx accessory protein, Gene Therapy, vol.72, issue.5, 2012. ,
DOI : 10.1128/JVI.05384-11
Immunization with Pre-Erythrocytic Antigen CelTOS from
Plasmodium falciparum Elicits Cross-Species Protection
against Heterologous Challenge with Plasmodium
berghei, PLoS ONE, vol.9, issue.8, p.12294, 2010. ,
DOI : 10.1371/journal.pone.0012294.s002
HIV-1 Reverse Transcription A Termination Step at the Center of the Genome, Journal of Molecular Biology, vol.241, issue.5, pp.651-662, 1994. ,
DOI : 10.1006/jmbi.1994.1542
Simple Centrifugation Method for Rapid Separation of Sporozoites from Mosquitoes, The Journal of Parasitology, vol.70, issue.5, pp.831-833, 1984. ,
DOI : 10.2307/3281779
The Effects of radiation on the safety and protective efficacy of an attenuated Plasmodium yoelii sporozoite malaria vaccine, Vaccine, vol.27, issue.27, pp.3675-3680, 2009. ,
DOI : 10.1016/j.vaccine.2008.11.073
Immune responses to defined epitopes of the circumsporozoite protein of the murine malaria parasite,Plasmodium yoelii, European Journal of Immunology, vol.7, issue.6, pp.1215-1222, 1990. ,
DOI : 10.1002/eji.1830200604
Plasmid Vector-Linked Maturation of Natural Killer (NK) Cells Is Coupled to Antigen-Dependent NK Cell Activation during DNA-Based Immunization in Mice, Journal of Virology, vol.85, issue.19, 2011. ,
DOI : 10.1128/JVI.00062-11