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Journal articles
Pyrazole-3/5-carboxylic acids from 3/5-trifluoromethyl NH-pyrazoles
Abstract : We report here the transformation of 3/5-trifluoromethylpyrazoles derivative into the corresponding NH-pyrazole-3/5-carboxylic acids. Moreover, from 4- or 5-iodinated-3/5-trifluoromethylpyrazoles building blocks and the use of SuzukieMiyaura or Negishi reactions followed by the trifluoromethyl hydrolysis, we illustrate short and original accesses to many series of NH-pyrazole-3/5-carboxylic acids otherwise difficult to prepare.
https://hal-pasteur.archives-ouvertes.fr/pasteur-00755935
Contributor : Yves Janin <>
Submitted on : Thursday, November 22, 2012 - 11:02:44 AM
Last modification on : Saturday, July 3, 2021 - 3:44:36 AM
Contributor : Yves Janin <>
Submitted on : Thursday, November 22, 2012 - 11:02:44 AM
Last modification on : Saturday, July 3, 2021 - 3:44:36 AM