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Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses.

Abstract : ABSTRACT: Autophagy is a protein degradative process important for normal cellular metabolism. It is apparently used also by cells to eliminate invading pathogens. Interestingly, many pathogens have learned to subvert the cell's autophagic process. Here, we review the interactions between viruses and cells in regards to cellular autophagy. Using findings from hepatitis B virus and human retroviruses, HIV-1 and HTLV-1, we discuss mechanisms used by viruses to usurp cellular autophagy in ways that benefit viral replication.
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Submitted on : Sunday, November 11, 2012 - 1:02:41 AM
Last modification on : Monday, January 13, 2020 - 5:08:08 PM
Long-term archiving on: : Tuesday, February 12, 2013 - 2:40:10 AM

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Sai-Wen Tang, Aurelie Ducroux, Kuan-Teh Jeang, Christine Neuveut. Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses.. Journal of Biomedical Science, BioMed Central, 2012, 19 (1), pp.92. ⟨10.1186/1423-0127-19-92⟩. ⟨pasteur-00750566⟩

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