The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden, Am J Trop Med Hyg, vol.64, pp.1-11, 2001. ,
In-hospital morbidity and mortality due to severe malarial anemia in western Kenya, Am J Trop Med Hyg, vol.77, pp.23-28, 2007. ,
Severe Malarial Anaemia, Current Molecular Medicine, vol.6, issue.2, pp.155-168, 2006. ,
DOI : 10.2174/156652406776055159
Malaria, erythrocytic infection, and anemia, Hematology, vol.2009, issue.1, pp.87-93, 2009. ,
DOI : 10.1182/asheducation-2009.1.87
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933134
Low plasma concentrations of interleukin 10 in severe malarial anaemia compared to cerebral and uncomplicated malaria. The Lancet, pp.1768-1772, 1998. ,
A Low Interleukin???10 Tumor Necrosis Factor????? Ratio Is Associated with Malaria Anemia in Children Residing in a Holoendemic Malaria Region in Western Kenya, The Journal of Infectious Diseases, vol.179, issue.1, pp.279-282, 1999. ,
DOI : 10.1086/314548
Plasmodium chabaudi chabaudi:Differential Susceptibility of Gene-Targeted Mice Deficient in IL-10 to an Erythrocytic-Stage Infection, Experimental Parasitology, vol.84, issue.2, pp.253-263, 1996. ,
DOI : 10.1006/expr.1996.0111
Pathology of Plasmodium chabaudi chabaudi Infection and Mortality in Interleukin-10-Deficient Mice Are Ameliorated by Anti-Tumor Necrosis Factor Alpha and Exacerbated by Anti-Transforming Growth Factor ?? Antibodies, Infection and Immunity, vol.71, issue.9, pp.4850-4856, 2003. ,
DOI : 10.1128/IAI.71.9.4850-4856.2003
Mechanisms of erythroid suppression in the anemia of chronic disease, Blood Cells, vol.13, pp.171-184, 1987. ,
Hepcidin and Cytokines in Anaemia, Hematology, vol.102, issue.1, pp.357-362, 2004. ,
DOI : 10.1172/JCI21441
Interferon gamma and tumour necrosis factor alpha are overexpressed in bone marrow T lymphocytes from paediatric patients with aplastic anaemia, British Journal of Haematology, vol.78, issue.4, pp.1023-1031, 2001. ,
DOI : 10.1056/NEJM199705083361906
TNF-?? and IFN-?? are overexpressed in the bone marrow of Fanconi anemia patients and TNF-?? suppresses erythropoiesis in vitro, Blood, vol.102, issue.6, pp.2053-2059, 2003. ,
DOI : 10.1182/blood-2003-01-0114
Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1, Nature, vol.401, issue.6752, pp.489-493, 1999. ,
DOI : 10.1038/46809
Reduction of cell cycle progression in human erythroid progenitor cells treated with tumour necrosis factor alpha occurs with reduced CDK6 and is partially reversed by CDK6 transduction, British Journal of Haematology, vol.13, issue.6, pp.919-927, 2003. ,
DOI : 10.1016/S0165-5728(99)00278-7
Erythroblastic islands: niches for erythropoiesis, Blood, vol.112, issue.3, pp.470-478, 2008. ,
DOI : 10.1182/blood-2008-03-077883
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481536
Urinary neopterin is elevated in patients with malaria, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol.78, issue.4, pp.545-546, 1984. ,
DOI : 10.1016/0035-9203(84)90080-4
Macrophage activation in falciparum malaria as measured by neopterin and interferon-gamma, Clinical & Experimental Immunology, vol.10, issue.1, pp.97-101, 1990. ,
DOI : 10.1111/j.1365-2249.1990.tb05410.x
Prolonged macrophage activation and persistent anaemia in children with complicated malaria, Tropical Medicine and International Health, vol.3, issue.1, pp.60-65, 1998. ,
DOI : 10.1046/j.1365-3156.1998.00168.x
Red cell surface changes and erythrophagocytosis in children with severe Plasmodium falciparum anemia, Blood, vol.95, pp.1481-1486, 2000. ,
The importance of strict patient definitions in studies of malaria pathogenesis, Trends in Parasitology, vol.17, issue.7, pp.313-314, 2001. ,
DOI : 10.1016/S1471-4922(01)01950-X
Distinct patterns of cytokine regulation in discrete clinical forms of P. falciparum malaria, Eur Cytokine Netw, vol.11, pp.113-118, 2000. ,
Monocyte HLA-DR antigen expression characterizes clinical outcome in the trauma patient, British Journal of Surgery, vol.126, issue.2, pp.204-207, 1990. ,
DOI : 10.1002/bjs.1800770225
Transmission of Signals from the T Lymphocyte Antigen Receptor to the Genes Responsible for Cell Proliferation and Immune Function: The Missing Link, Annual Review of Immunology, vol.8, issue.1, pp.421-452, 1990. ,
DOI : 10.1146/annurev.iy.08.040190.002225
Association of intraleukocytic Plasmodium falciparum malaria pigment with disease severity, clinical manifestations and prognosis in severe malaria, Am J Trop Med Hyg, vol.69, pp.253-259, 2003. ,
Phagocytosis of the malaria pigment, haemozoin, impairs expression of major histocompatibility complex class II antigen, CD54 and CD11c in human monocytes, Infect Immun, vol.66, pp.1601-1606, 1998. ,
A model of human whole blood lymphokine release for in vitro and ex vivo use, Journal of Immunological Methods, vol.275, issue.1-2, pp.69-79, 2003. ,
DOI : 10.1016/S0022-1759(03)00003-6
Direct stimulation of cytokines (IL-1??, TNF-??, IL-6, IL-2, IFN-?? and GM-CSF) in whole blood. I. Comparison with isolated PBMC stimulation, Cytokine, vol.4, issue.3, pp.239-248, 1992. ,
DOI : 10.1016/1043-4666(92)90062-V
Distinct Clinical and Immunologic Profiles in Severe Malarial Anemia and Cerebral Malaria in Zambia, Journal of Infectious Diseases, vol.203, issue.2, pp.211-219, 2011. ,
DOI : 10.1093/infdis/jiq041
Cellular immune responses to Plasmodium falciparum antigens in Gambian children during and after an acute attack of falciparum malaria, Clin Exp Immunol, vol.73, pp.17-22, 1988. ,
Modulation of cytokine profiles by malaria pigment ??? hemozoin: role of IL-10 in suppression of proliferative responses of mitogen stimulated human PBMC, Cytokine, vol.28, issue.6, pp.205-213, 2004. ,
DOI : 10.1016/j.cyto.2004.08.002
Acquisition of Hemozoin by Monocytes Down-Regulates Interleukin-12 p40 (IL-12p40) Transcripts and Circulating IL-12p70 through an IL-10-Dependent Mechanism: In Vivo and In Vitro Findings in Severe Malarial Anemia, Infection and Immunity, vol.74, issue.9, pp.5249-5260, 2006. ,
DOI : 10.1128/IAI.00843-06
In vivo acquisition of hemozoin by placental blood mononuclear cells suppresses PGE2, TNF-??, and IL-10, Biochemical and Biophysical Research Communications, vol.311, issue.4, pp.839-846, 2003. ,
DOI : 10.1016/j.bbrc.2003.10.073
Impairment of macrophage functions after ingestion of Plasmodium falciparum-infected erythrocytes or isolated malarial pigment [published erratum appears in J Exp Med 1993 Mar 1;177(3):following 873], Journal of Experimental Medicine, vol.176, issue.4, pp.1033-1041, 1992. ,
DOI : 10.1084/jem.176.4.1033
Hemozoin and the human monocyte?a brief review of their interactions, Parassitologia, vol.50, pp.143-145, 2008. ,
Suppression of erythropoiesis in malarial anemia is associated with hemozoin in vitro and in vivo, Blood, vol.108, issue.8, pp.2569-2577, 2006. ,
DOI : 10.1182/blood-2006-05-018697
Clearance kinetics of parasites and pigment-containing leucocytes in severe malaria, Blood, vol.88, pp.4694-4700, 1996. ,
A role for CD36 in the regulation of dendritic cell function, Proceedings of the National Academy of Sciences, vol.98, issue.15, pp.8750-8755, 2001. ,
DOI : 10.1073/pnas.151028698
Malaria, monocytes, macrophages and myeloid dendritic cells: sticking of infected erythrocytes switches off host cells, Current Opinion in Immunology, vol.14, issue.4, pp.458-465, 2002. ,
DOI : 10.1016/S0952-7915(02)00368-0
The Frequency of BDCA3-Positive Dendritic Cells Is Increased in the Peripheral Circulation of Kenyan Children with Severe Malaria, Infection and Immunity, vol.74, issue.12, pp.6700-6706, 2006. ,
DOI : 10.1128/IAI.00861-06
Cytoadherence characteristics of Plasmodium falciparum-infected erythrocytes from malawian children with severe and uncomplicated malaria, Am J Trop Med Hyg, vol.61, pp.467-472, 1999. ,
Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparumparasitized erythrocytes: a role for CD36 in malarial clearance, Blood, vol.96, pp.3231-3240, 2000. ,
IL-10: The Master Regulator of Immunity to Infection, The Journal of Immunology, vol.180, issue.9, pp.5771-5777, 2008. ,
DOI : 10.4049/jimmunol.180.9.5771
IL-10 from CD4+CD25???Foxp3???CD127??? Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection, PLoS Pathogens, vol.10, issue.2, p.1000004, 2008. ,
DOI : 10.1371/journal.ppat.1000004.s003
Severe malarial anemia of low parasite burden in rodent models results from accelerated clearance of uninfected erythrocytes, Blood, vol.107, issue.3, pp.1192-1199, 2006. ,
DOI : 10.1182/blood-2005-08-3460
The CD14+ CD16+ blood monocytes: their role in infection and inflammation, Journal of Leukocyte Biology, vol.81, issue.3, pp.584-592, 2007. ,
DOI : 10.1189/jlb.0806510
The Levels of CD16/Fc?? Receptor IIIA on CD14+ CD16+ Monocytes Are Higher in Children with Severe Plasmodium falciparum Anemia than in Children with Cerebral or Uncomplicated Malaria, Infection and Immunity, vol.78, issue.5, pp.2173-2181, 2010. ,
DOI : 10.1128/IAI.01078-09
Peripheral blood dendritic cells in children with acute Plasmodium falciparum malaria, Blood, vol.98, issue.9, pp.2859-2861, 2001. ,
DOI : 10.1182/blood.V98.9.2859
Role of Interleukin-10 in the Intracellular Sequestration of Human Leukocyte Antigen-DR in Monocytes during Septic Shock, American Journal of Respiratory and Critical Care Medicine, vol.166, issue.11, pp.1475-1482, 2002. ,
DOI : 10.1164/rccm.200203-217OC
Clinical Aspects: From Systemic Inflammation to 'Immunoparalysis???, Chem Immunol, vol.74, pp.162-177, 2000. ,
DOI : 10.1159/000058753
Reprogramming of circulatory cells in sepsis and SIRS, Journal of Endotoxin Research, vol.11, issue.5, pp.311-320, 2005. ,
DOI : 10.1177/09680519050110050901
Determining the Degree of Immunodysregulation in Sepsis, Contrib Nephrol, vol.156, pp.101-111, 2007. ,
DOI : 10.1159/000102075
Endotoxin tolerance: new mechanisms, molecules and clinical significance, Trends in Immunology, vol.30, issue.10, pp.475-487, 2009. ,
DOI : 10.1016/j.it.2009.07.009
Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria, Proceedings of the National Academy of Sciences, vol.103, issue.1, pp.177-182, 2006. ,
DOI : 10.1073/pnas.0506803102
Plasmodium falciparum Infection Causes Proinflammatory Priming of Human TLR Responses, The Journal of Immunology, vol.179, issue.1, pp.162-171, 2007. ,
DOI : 10.4049/jimmunol.179.1.162