High level of inter-species transmission of simian foamy virus from non-human primates to humans in Gabon, central Africa

Augustin Mouinga-Ondémé (1) , Mélanie Caron (1) , Antoine Gessain (2) , Mirdad Kazanji (1, 3)

1 Unité de Rétrovirologie
2 Epidémiologie et Physiopathologie des Virus Oncogènes
3 Institut Pasteur de Bangui

Each of the pathogenic human retroviruses (HIV-1/2 and HTLV-1) has a non-human primate (NHP) counterpart, and the presence of these retroviruses in humans results from interspecies transmission. The passage of another simian retrovirus, simian foamy virus (SFV), from NHPs to humans has been reported. Here, we evaluated the natural history of SFV in a free-ranging colony of mandrills (CIRMF primate center) and in mandrills living in natura in Gabon (central Africa). We also determined the SFV prevalence in a series of 497 NHP living in different parts of Gabon. Lastly, we investigated the possible transmission of SFVs to humans.

Domaines: Maladies infectieuses

Augustin Mouinga-Ondémé, Mélanie Caron, Antoine Gessain, Mirdad Kazanji. High level of inter-species transmission of simian foamy virus from non-human primates to humans in Gabon, central Africa. Retrovirology, 2011, 8 (Suppl 1), pp.A229. ⟨10.1186/1742-4690-8-S1-A229⟩. ⟨pasteur-00733980⟩