R. Kopan and M. X. Ilagan, The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism, Cell, vol.137, issue.2, pp.216-233, 2009.
DOI : 10.1016/j.cell.2009.03.045

F. A. High and J. A. Epstein, The multifaceted role of Notch in cardiac development and disease, Nature Reviews Genetics, vol.96, issue.1, pp.49-61, 2008.
DOI : 10.1038/nrg2279

F. Logeat, C. Bessia, C. Brou, O. Lebail, S. Jarriault et al., The Notch1 receptor is cleaved constitutively by a furin-like convertase, Proceedings of the National Academy of Sciences, vol.95, issue.14, pp.8108-8112, 1998.
DOI : 10.1073/pnas.95.14.8108

N. Vodovar and F. Schweisguth, Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?, Journal of Biology, vol.7, issue.2, 2008.
DOI : 10.1186/jbiol68

S. F. Heuss, D. Ndiaye-lobry, E. M. Six, A. Israël, and F. Logeat, The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity, Proceedings of the National Academy of Sciences, vol.105, issue.32, pp.11212-11217, 2008.
DOI : 10.1073/pnas.0800695105

URL : https://hal.archives-ouvertes.fr/pasteur-00336966

C. Brou, Intracellular trafficking of Notch receptors and ligands, Experimental Cell Research, vol.315, issue.9, pp.1549-1555, 2009.
DOI : 10.1016/j.yexcr.2008.09.010

A. M. Dirac, S. M. Nijman, T. R. Brummelkamp, and R. Bernards, Functional Annotation of Deubiquitinating Enzymes Using RNA Interference, Methods Enzymol, vol.398, pp.554-567, 2005.
DOI : 10.1016/S0076-6879(05)98045-2

J. Moretti, P. Chastagner, S. Gastaldello, S. F. Heuss, A. M. Dirac et al., The Translation Initiation Factor 3f (eIF3f) Exhibits a Deubiquitinase Activity Regulating Notch Activation, PLoS Biology, vol.95, issue.11, p.1000545, 2010.
DOI : 10.1371/journal.pbio.1000545.s005

URL : https://hal.archives-ouvertes.fr/pasteur-00539184

P. Chastagner, A. Israël, and C. Brou, AIP4/Itch Regulates Notch Receptor Degradation in the Absence of Ligand, PLoS ONE, vol.64, issue.7, p.2735, 2008.
DOI : 10.1371/journal.pone.0002735.s004

URL : https://hal.archives-ouvertes.fr/pasteur-00307917

E. M. Six, D. Ndiaye, G. Sauer, Y. Laâbi, R. Athman et al., The Notch Ligand Delta1 Recruits Dlg1 at Cell-Cell Contacts and Regulates Cell Migration, Journal of Biological Chemistry, vol.279, issue.53, pp.55818-55826, 2004.
DOI : 10.1074/jbc.M408022200

C. Brou, F. Logeat, N. Gupta, C. Bessia, O. Lebail et al., A Novel Proteolytic Cleavage Involved in Notch Signaling, Molecular Cell, vol.5, issue.2, pp.207-216, 2000.
DOI : 10.1016/S1097-2765(00)80417-7

E. H. Schroeter, J. A. Kisslinger, and R. Kopan, Notch-1 signaling requires ligand-induced proteolytic release of intracellular domain, Nature, vol.393, pp.382-386, 1998.

M. A. Cohn, Y. Kee, W. Haas, S. P. Gygi, D. Andrea et al., UAF1 Is a Subunit of Multiple Deubiquitinating Enzyme Complexes, Journal of Biological Chemistry, vol.284, issue.8, pp.5343-5351, 2009.
DOI : 10.1074/jbc.M808430200

S. Minoguchi, Y. Taniguchi, H. Kato, T. Okazaki, L. J. Strobl et al., RBP-L, a transcription factor related to RBP-Jkappa., Molecular and Cellular Biology, vol.17, issue.5, pp.2679-2687, 1997.
DOI : 10.1128/MCB.17.5.2679

M. A. Cohn, P. Kowal, K. Yang, W. Haas, T. T. Huang et al., A UAF1-Containing Multisubunit Protein Complex Regulates the Fanconi Anemia Pathway, Molecular Cell, vol.28, issue.5, pp.786-797, 2007.
DOI : 10.1016/j.molcel.2007.09.031

P. E. Row, I. A. Prior, J. Mccullough, M. J. Clague, and S. Urbé, The Ubiquitin Isopeptidase UBPY Regulates Endosomal Ubiquitin Dynamics and Is Essential for Receptor Down-regulation, Journal of Biological Chemistry, vol.281, issue.18, pp.12618-12624, 2006.
DOI : 10.1074/jbc.M512615200

L. Couturier, N. Vodovar, and F. Schweisguth, Endocytosis by Numb breaks Notch symmetry at??cytokinesis, Nature Cell Biology, vol.122, issue.2, pp.131-139, 2012.
DOI : 10.1038/35050558

N. Gupta-rossi, E. Six, O. Lebail, F. Logeat, P. Chastagner et al., Monoubiquitination and endocytosis direct ??-secretase cleavage of activated Notch receptor, The Journal of Cell Biology, vol.127, issue.1, pp.73-83, 2004.
DOI : 10.1074/jbc.273.20.12436

URL : https://hal.archives-ouvertes.fr/pasteur-00583271

J. L. Mummery-widmer, M. Yamazaki, T. Stoeger, M. Novatchkova, S. Bhalerao et al., Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi, Nature, vol.314, issue.7241, pp.987-992, 2009.
DOI : 10.1038/nature07936

A. B. Babaoglan, K. M. O-'connor-giles, H. Mistry, A. Schickedanz, B. A. Wilson et al., Sanpodo: a context-dependent activator and inhibitor of Notch signaling during asymmetric divisions, Development, vol.136, issue.24, pp.4089-4098, 2009.
DOI : 10.1242/dev.040386

T. Ravid, J. M. Heidinger, P. Gee, E. M. Khan, and T. Goldkorn, c-Cbl-mediated Ubiquitinylation Is Required for Epidermal Growth Factor Receptor Exit from the Early Endosomes, Journal of Biological Chemistry, vol.279, issue.35, pp.37153-37162, 2004.
DOI : 10.1074/jbc.M403210200

E. Stang, F. D. Blystad, M. Kazazic, V. Bertelsen, T. Brodahl et al., Cbl-dependent Ubiquitination Is Required for Progression of EGF Receptors into Clathrin-coated Pits, Molecular Biology of the Cell, vol.15, issue.8, pp.3591-3604, 2004.
DOI : 10.1091/mbc.E04-01-0041

H. A. Alwan and J. E. Van-leeuwen, UBPY-mediated Epidermal Growth Factor Receptor (EGFR) De-ubiquitination Promotes EGFR Degradation, Journal of Biological Chemistry, vol.282, issue.3, pp.1658-1669, 2007.
DOI : 10.1074/jbc.M604711200

URL : http://repository.ubn.ru.nl/bitstream/2066/36647/1/36647.pdf

D. Komander, M. J. Clague, and S. Urbé, Breaking the chains: structure and function of the deubiquitinases, Nature Reviews Molecular Cell Biology, vol.280, issue.8, pp.550-563, 2009.
DOI : 10.1038/nrm2731

M. E. Sowa, E. J. Bennett, S. P. Gygi, and J. W. Harper, Defining the Human Deubiquitinating Enzyme Interaction Landscape, Cell, vol.138, issue.2, pp.389-403, 2009.
DOI : 10.1016/j.cell.2009.04.042

A. Saj, Z. Arziman, D. Stempfle, W. Van-belle, U. Sauder et al., A Combined Ex Vivo and In Vivo RNAi Screen for Notch Regulators in Drosophila Reveals an Extensive Notch Interaction Network, Developmental Cell, vol.18, issue.5, pp.862-876, 2010.
DOI : 10.1016/j.devcel.2010.03.013

T. Mund and H. Pelham, Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins, EMBO reports, vol.446, issue.5, pp.501-507, 2009.
DOI : 10.1038/23293

H. Y. Joo, A. Jones, C. Yang, L. Zhai, A. D. Smith et al., Regulation of Histone H2A and H2B Deubiquitination and Xenopus Development by USP12 and USP46, Journal of Biological Chemistry, vol.286, issue.9, pp.7190-7201, 2011.
DOI : 10.1074/jbc.M110.158311

A. C. Faesen, M. P. Luna-vargas, P. P. Geurink, M. Clerici, R. Merkx et al., The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types, Chemistry & Biology, vol.18, issue.12, pp.1550-1561, 2011.
DOI : 10.1016/j.chembiol.2011.10.017