A. R. Almeida, J. A. Borghans, and A. A. Freitas, T Cell Homeostasis, The Journal of Experimental Medicine, vol.133, issue.5, pp.591-599, 2001.
DOI : 10.1182/blood.V97.10.2983
URL : https://hal.archives-ouvertes.fr/pasteur-00327507

A. R. Almeida, N. Legrand, M. Papiernik, and A. A. Freitas, Homeostasis of Peripheral CD4+ T Cells: IL-2R?? and IL-2 Shape a Population of Regulatory Cells That Controls CD4+ T Cell Numbers, The Journal of Immunology, vol.169, issue.9, pp.4850-4860, 2002.
DOI : 10.4049/jimmunol.169.9.4850
URL : https://hal.archives-ouvertes.fr/pasteur-00327445

A. R. Almeida, B. Rocha, A. A. Freitas, and C. Tanchot, Homeostasis of T cell numbers: from thymus production to peripheral compartmentalization and the indexation of regulatory T cells, Seminars in Immunology, vol.17, issue.3, pp.239-249, 2005.
DOI : 10.1016/j.smim.2005.02.002
URL : https://hal.archives-ouvertes.fr/pasteur-00019660

A. R. Almeida, B. Zaragoza, and A. A. Freitas, Competition controls the rate of transition between the peripheral pools of CD4+CD25- and CD4+CD25+ T cells, International Immunology, vol.18, issue.11, pp.1607-1613, 2006.
DOI : 10.1093/intimm/dxl093
URL : https://hal.archives-ouvertes.fr/pasteur-00161685

A. R. Almeida, B. Zaragoza, and A. A. Freitas, Indexation as a Novel Mechanism of Lymphocyte Homeostasis: The Number of CD4+CD25+ Regulatory T Cells Is Indexed to the Number of IL-2-Producing Cells, The Journal of Immunology, vol.177, issue.1, pp.192-200, 2006.
DOI : 10.4049/jimmunol.177.1.192
URL : https://hal.archives-ouvertes.fr/pasteur-00161683

O. Annacker, O. Burlen-defranoux, R. Pimenta-araujo, A. Cumano, and A. Bandeira, Regulatory CD4 T Cells Control the Size of the Peripheral Activated/Memory CD4 T Cell Compartment, The Journal of Immunology, vol.164, issue.7, pp.3573-3580, 2000.
DOI : 10.4049/jimmunol.164.7.3573

P. A. Antony, C. A. Piccirillo, A. Akpinarli, S. E. Finkelstein, P. J. Speiss et al., CD8+ T Cell Immunity Against a Tumor/Self-Antigen Is Augmented by CD4+ T Helper Cells and Hindered by Naturally Occurring T Regulatory Cells, The Journal of Immunology, vol.174, issue.5, pp.2591-2601, 2005.
DOI : 10.4049/jimmunol.174.5.2591

M. Asano, M. Toda, N. Sakaguchi, and S. Sakaguchi, Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation, Journal of Experimental Medicine, vol.184, issue.2, pp.387-396, 1996.
DOI : 10.1084/jem.184.2.387

T. Barthlott, G. Kassiotis, and B. Stockinger, T Cell Regulation as a Side Effect of Homeostasis and Competition, The Journal of Experimental Medicine, vol.163, issue.4, pp.451-460, 2003.
DOI : 10.1006/smim.2000.0232

A. L. Bayer, A. Yu, D. Adeegbe, and T. R. Malek, T regulatory cell development during the neonatal period, The Journal of Experimental Medicine, vol.155, issue.5, pp.769-777, 2005.
DOI : 10.1016/S0014-5793(97)00313-X

Y. Belkaid and B. T. Rouse, Natural regulatory T cells in infectious disease, Nature Immunology, vol.172, issue.4, pp.353-360, 2005.
DOI : 10.1126/science.1079490

C. L. Bennett, J. Christie, F. Ramsdell, M. E. Brunkow, P. J. Ferguson et al., The immune dysregulation , polyendocrinopathy, enteropathy , X-linked syndrome (IPEX) is caused by mutations of FOXP3, Nat. Genet, vol.27, pp.20-21, 2001.

C. Bernard, Introduction À L'étude de la Médecine Expérimentale, Paris: J.-B, 1865.
DOI : 10.14375/NP.9782081307582

S. P. Berzins, R. L. Boyd, and J. F. Miller, The Role of the Thymus and Recent Thymic Migrants in the Maintenance of the Adult Peripheral Lymphocyte Pool, The Journal of Experimental Medicine, vol.159, issue.11, pp.1839-1848, 1998.
DOI : 10.1046/j.1365-2567.1996.d01-764.x

G. Bocharov, J. Quiel, T. Luzyanina, H. Alon, E. Chiglintsev et al., Feedback regulation of proliferation vs. differentiation rates explains the dependence of CD4 T-cell expansion on precursor number, Proceedings of the National Academy of Sciences, vol.108, issue.8, pp.3318-3323, 2011.
DOI : 10.1073/pnas.1019706108

O. Boyman, M. Kovar, M. P. Rubinstein, C. D. Surh, and J. Sprent, Selective Stimulation of T Cell Subsets with Antibody-Cytokine Immune Complexes, Science, vol.311, issue.5769, pp.1924-1927, 2006.
DOI : 10.1126/science.1122927

T. Brocker, Survival of Mature CD4 T Lymphocytes Is Dependent on Major Histocompatibility Complex Class II???expressing Dendritic Cells, The Journal of Experimental Medicine, vol.14, issue.8, pp.1223-1232, 1997.
DOI : 10.1146/annurev.iy.09.040191.001415

M. A. Burchill, J. Yang, C. Vogtenhuber, B. R. Blazar, and M. A. Farrar, IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells, 2007.

N. J. Burroughs, M. F. Ferreira, B. Oliveira, and A. A. Pinto, Autoimmunity arising from bystander proliferation of T cells in an immune response model, Mathematical and Computer Modelling, vol.53, issue.7-8, pp.1389-1393, 2011.
DOI : 10.1016/j.mcm.2010.01.020

D. Busse, M. De-la-rosa, K. Hobiger, K. Thurley, M. Flossdorf et al., Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments, Proceedings of the National Academy of Sciences, vol.107, issue.7, pp.3058-3063, 2010.
DOI : 10.1073/pnas.0812851107

W. Cannon, The Wisdom of the Body, 1932.

J. Carneiro, K. Leon, I. Caramalho, C. Van-den-dool, R. Gardner et al., T cells, Immunological Reviews, vol.6, issue.1, pp.48-68, 2007.
DOI : 10.1111/j.1600-065X.2007.00487.x

A. Chaudhry, R. M. Samstein, P. Treuting, Y. Liang, M. C. Pils et al., Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation, Immunity, vol.34, issue.4, pp.566-578, 2011.
DOI : 10.1016/j.immuni.2011.03.018

Y. Chen, C. J. Haines, I. Gutcher, K. Hochweller, W. M. Blumenschein et al., Foxp3+ Regulatory T Cells Promote T Helper 17 Cell Development In??Vivo through Regulation of Interleukin-2, Immunity, vol.34, issue.3, pp.409-421, 2011.
DOI : 10.1016/j.immuni.2011.02.011

B. S. Cobb, A. Hertweck, J. Smith, E. O-'connor, D. Graf et al., A role for Dicer in immune regulation, The Journal of Experimental Medicine, vol.27, issue.11, pp.2519-2527, 2006.
DOI : 10.1101/gad.816400

M. A. Curotto-de-lafaille, A. C. Lino, N. Kutchukhidze, and J. J. Lafaille, CD25- T Cells Generate CD25+Foxp3+ Regulatory T Cells by Peripheral Expansion, The Journal of Immunology, vol.173, issue.12, pp.7259-7268, 2004.
DOI : 10.4049/jimmunol.173.12.7259

A. A. De-freitas, Tractus Immuno-Logicus: A Brief History of the Immune System, 2009.

S. P. Diggle, A. S. Griffin, G. S. Campbell, and S. A. West, Cooperation and conflict in quorum-sensing bacterial populations, Nature, vol.184, issue.7168, pp.411-414, 2007.
DOI : 10.1038/nature06279

|. Frontiers-in-immunology, Z. Fehervari, T. Yamaguchi, and S. Sakaguchi, The dichotomous role of IL-2: tolerance versus immunity, Trends Immunol, vol.27, pp.109-111, 2006.

O. Feinerman, G. Jentsch, K. E. Tkach, J. W. Coward, M. M. Hathorn et al., Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response, Molecular Systems Biology, vol.175, p.437, 2010.
DOI : 10.1038/ng1958

J. D. Fontenot, M. A. Gavin, and A. Y. Rudensky, Foxp3 programs the development and function of CD4+CD25+ regulatory T cells, Nature Immunology, vol.4, issue.4, pp.330-336, 2003.
DOI : 10.1038/ni904

J. D. Fontenot, J. P. Rasmussen, M. A. Gavin, and A. Y. Rudensky, A function for interleukin 2 in Foxp3-expressing regulatory T cells, Nature Immunology, vol.171, issue.11, pp.1142-1151, 2005.
DOI : 10.1186/gb-2004-5-10-r80

J. D. Fontenot, J. P. Rasmussen, L. M. Williams, J. L. Dooley, A. G. Farr et al., Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3, Immunity, vol.22, issue.3, pp.329-341, 2005.
DOI : 10.1016/j.immuni.2005.01.016

A. A. Freitas, F. Agenes, C. , and G. C. , Cellular competition modulates survival and selection of CD8+ T cells, European Journal of Immunology, vol.183, issue.11, pp.2640-2649, 1996.
DOI : 10.1002/eji.1830261115
URL : https://hal.archives-ouvertes.fr/pasteur-00329372

A. A. Freitas and B. Rocha, Population Biology of Lymphocytes: The Flight for Survival, Annual Review of Immunology, vol.18, issue.1, pp.83-111, 2000.
DOI : 10.1146/annurev.immunol.18.1.83
URL : https://hal.archives-ouvertes.fr/hal-00108283

A. A. Freitas and B. Rocha, Homeostasis of naive T cells: the Foxo that fixes, Nature Immunology, vol.178, issue.2, pp.133-134, 2009.
DOI : 10.1038/ni1565
URL : https://hal.archives-ouvertes.fr/pasteur-00356174

M. A. Gavin, S. R. Clarke, E. Negrou, A. Gallegos, and A. Rudensky, Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo, Nature Immunology, vol.3, issue.1, pp.33-41, 2002.
DOI : 10.1038/ni743

P. K. Gregersen and L. M. Olsson, Recent Advances in the Genetics of Autoimmune Disease, Annual Review of Immunology, vol.27, issue.1, pp.363-391, 2009.
DOI : 10.1146/annurev.immunol.021908.132653

Y. Grinberg-bleyer, A. Baeyens, S. You, R. Elhage, G. Fourcade et al., IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells, The Journal of Experimental Medicine, vol.207, issue.9, pp.1871-1878, 2010.
DOI : 10.1038/ni.1774

M. Guimond, R. G. Veenstra, D. J. Grindler, H. Zhang, Y. Cui et al., Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells, Nature Immunology, vol.178, issue.2, pp.149-157, 2009.
DOI : 10.1038/sj.leu.2403770

J. A. Hill, M. Feuerer, K. Tash, S. Haxhinasto, J. Perez et al., Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional Signature, Immunity, vol.27, issue.5, pp.786-800, 2007.
DOI : 10.1016/j.immuni.2007.09.010

S. Hori, T. Nomura, and S. Sakaguchi, Control of Regulatory T Cell Development by the Transcription Factor Foxp3, Science, vol.299, issue.5609, pp.1057-1061, 2003.
DOI : 10.1126/science.1079490

C. T. Huang, C. J. Workman, D. Flies, X. Pan, A. L. Marson et al., Role of LAG-3 in Regulatory T Cells, Immunity, vol.21, issue.4, pp.503-513, 2004.
DOI : 10.1016/j.immuni.2004.08.010

S. Huber, N. Gagliani, E. Esplugues, W. O-'connor, . Jr et al., Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3??? and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner, Immunity, vol.34, issue.4, pp.554-565, 2011.
DOI : 10.1016/j.immuni.2011.01.020

V. Kalia, S. Sarkar, S. Subramaniam, W. N. Haining, K. A. Smith et al., Prolonged Interleukin-2R?? Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo, Immunity, vol.32, issue.1, pp.91-103, 2010.
DOI : 10.1016/j.immuni.2009.11.010

Y. M. Kerdiles, D. R. Beisner, R. Tinoco, A. S. Dejean, D. H. Castrillon et al., Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor, Nature Immunology, vol.174, issue.2, pp.176-184, 2009.
DOI : 10.1038/ni1513

R. Khattri, D. Kasprowicz, T. Cox, M. Mortrud, M. W. Appleby et al., The Amount of Scurfin Protein Determines Peripheral T Cell Number and Responsiveness, The Journal of Immunology, vol.167, issue.11, pp.6312-6320, 2001.
DOI : 10.4049/jimmunol.167.11.6312

J. M. Kim, J. P. Rasmussen, and A. Y. Rudensky, Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice, Nature Immunology, vol.167, issue.2, pp.191-197, 2007.
DOI : 10.1038/ni1289

P. S. Kim, P. P. Lee, and D. Levy, Modeling regulation mechanisms in the immune system, Journal of Theoretical Biology, vol.246, issue.1, pp.33-69, 2007.
DOI : 10.1016/j.jtbi.2006.12.012

J. Kirberg, A. Berns, V. Boehmer, and H. , Peripheral T Cell Survival Requires Continual Ligation of the T Cell Receptor to Major Histocompatibility Complex???Encoded Molecules, The Journal of Experimental Medicine, vol.157, issue.8, pp.1269-1275, 1997.
DOI : 10.1038/383081a0

B. Knoechel, J. Lohr, E. Kahn, J. A. Bluestone, and A. K. Abbas, Sequential development of interleukin 2???dependent effector and regulatory T cells in response to endogenous systemic antigen, The Journal of Experimental Medicine, vol.14, issue.10, pp.1375-1386, 2005.
DOI : 10.1038/ni909

N. Komatsu, M. E. Mariotti-ferrandiz, Y. Wang, B. Malissen, H. Waldmann et al., T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity, Proceedings of the National Academy of Sciences, vol.106, issue.6, 1903.
DOI : 10.1073/pnas.0811556106
URL : https://hal.archives-ouvertes.fr/hal-00407810

T. M. Kundig, H. Schorle, M. F. Bachmann, H. Hengartner, R. M. Zinkernagel et al., Immune responses in interleukin-2-deficient mice, Science, vol.262, issue.5136, pp.1059-1061, 1993.
DOI : 10.1126/science.8235625

N. Labrecque, L. S. Whitfield, R. Obst, C. Waltzinger, C. Benoist et al., How Much TCR Does a T Cell Need?, Immunity, vol.15, issue.1, pp.71-82, 2001.
DOI : 10.1016/S1074-7613(01)00170-4

K. Lahl, C. Loddenkemper, C. Drouin, J. Freyer, J. Arnason et al., regulatory T cells induces a scurfy-like disease, The Journal of Experimental Medicine, vol.125, issue.1, pp.57-63, 2007.
DOI : 10.1126/science.1096472
URL : https://hal.archives-ouvertes.fr/pasteur-00161238

O. Lantz, I. Grandjean, P. Matzinger, D. Santo, and J. P. , Gamma chain required for naive CD4+ T cell survival but not for antigen proliferation, Nat. Immunol, vol.1, pp.54-58, 2000.

K. Leon, A. Lage, C. , and J. , Tolerance and immunity in a mathematical model of T-cell mediated suppression, Journal of Theoretical Biology, vol.225, issue.1, pp.107-126, 2003.
DOI : 10.1016/S0022-5193(03)00226-1

E. Leuchars, V. J. Wallis, M. J. Doenhoff, A. J. Davies, and J. Kruger, Studies of hyperthymic mice. I. The influence of multiple thymus grafts on the size of the peripheral T cell pool and immunological performance, Immunology, vol.35, pp.801-809, 1978.

A. Link, T. K. Vogt, S. Favre, M. R. Britschgi, H. Acha-orbea et al., Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells, Nature Immunology, vol.172, issue.11, pp.1255-1265, 2007.
DOI : 10.1038/ni1513

A. Liston, L. F. Lu, D. O-'carroll, A. Tarakhovsky, and A. Y. Rudensky, Dicer-dependent microRNA pathway safeguards regulatory T cell function, J. Exp. Med, vol.205, 1993.
DOI : 10.1084/jem.20081062
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526195

L. F. Lu, T. H. Thai, D. P. Calado, A. Chaudhry, M. Kubo et al., Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein, Immunity, vol.30, issue.1, pp.80-91, 2009.
DOI : 10.1016/j.immuni.2008.11.010

T. R. Malek, The Biology of Interleukin-2, Annual Review of Immunology, vol.26, issue.1, pp.453-479, 2008.
DOI : 10.1146/annurev.immunol.26.021607.090357

T. R. Malek and I. Castro, Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity, Immunity, vol.33, issue.2, pp.153-165, 2010.
DOI : 10.1016/j.immuni.2010.08.004

T. R. Malek, B. O. Porter, E. K. Codias, P. Scibelli, Y. et al., Normal Lymphoid Homeostasis and Lack of Lethal Autoimmunity in Mice Containing Mature T Cells with Severely Impaired IL-2 Receptors, The Journal of Immunology, vol.164, issue.6, pp.2905-2914, 2000.
DOI : 10.4049/jimmunol.164.6.2905

T. R. Malek, A. Yu, V. Vincek, P. Scibelli, and L. Kong, CD4 Regulatory T Cells Prevent Lethal Autoimmunity in IL-2R??-Deficient Mice, Immunity, vol.17, issue.2, pp.167-178, 2002.
DOI : 10.1016/S1074-7613(02)00367-9

K. J. Maloy and F. Powrie, Regulatory T cells in the control of immune pathology, Nature Immunology, vol.26, issue.9, pp.816-822, 2001.
DOI : 10.1038/ni0901-816

D. Metcalf, Multiple Thymus Grafts in Aged Mice, Nature, vol.93, issue.5005, pp.87-88, 1965.
DOI : 10.1038/208087a0

J. F. Miller, Effect of Thymectomy in Adult Mice on Immunological Responsiveness, Nature, vol.196, issue.5017, pp.1337-1338, 1965.
DOI : 10.1038/2081337a0

M. B. Miller and B. L. Bassler, Quorum Sensing in Bacteria, Annual Review of Microbiology, vol.55, issue.1, pp.165-199, 2001.
DOI : 10.1146/annurev.micro.55.1.165

R. Moriggl, D. J. Topham, S. Teglund, V. Sexl, C. Mckay et al., Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells, Immunity, vol.10, issue.2, pp.249-259, 1999.
DOI : 10.1016/S1074-7613(00)80025-4

B. H. Nelson and D. M. Willerford, Biology of the Interleukin-2 Receptor, Adv. Immunol, vol.70, pp.1-81, 1998.
DOI : 10.1016/S0065-2776(08)60386-7

M. Ono, H. Yaguchi, N. Ohkura, I. Kitabayashi, Y. Nagamura et al., Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1, Nature, vol.35, issue.7136, pp.685-689, 2007.
DOI : 10.1038/nature05673

W. Ouyang, O. Beckett, R. A. Flavell, and M. O. Li, An Essential Role of the Forkhead-Box Transcription Factor Foxo1 in Control of T Cell Homeostasis and Tolerance, Immunity, vol.30, issue.3, pp.358-371, 2009.
DOI : 10.1016/j.immuni.2009.02.003

P. Pandiyan, H. R. Conti, L. Zheng, A. C. Peterson, D. R. Mathern et al., CD4+CD25+Foxp3+ Regulatory T Cells Promote Th17 Cells In??Vitro and Enhance Host Resistance in Mouse Candida albicans Th17 Cell Infection Model, CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model, pp.422-434, 2011.
DOI : 10.1016/j.immuni.2011.03.002

M. E. Pipkin, J. A. Sacks, F. Cruz-guilloty, M. G. Lichtenheld, M. J. Bevan et al., Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells, Immunity, vol.32, issue.1, pp.79-90, 2010.
DOI : 10.1016/j.immuni.2009.11.012

B. Polic, D. Kunkel, A. Scheffold, R. , and K. , How ???? T cells deal with induced TCR?? ablation, Proceedings of the National Academy of Sciences, vol.98, issue.15, pp.8744-8749, 2001.
DOI : 10.1073/pnas.141218898

F. Powrie, M. W. Leach, S. Mauze, L. B. Caddle, and R. L. Coffman, mice, International Immunology, vol.5, issue.11, pp.1461-1471, 1993.
DOI : 10.1093/intimm/5.11.1461

J. Quiel, S. Caucheteux, A. Laurence, N. J. Singh, G. Bocharov et al., Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number, Proceedings of the National Academy of Sciences, vol.108, issue.8, pp.3312-3317, 2011.
DOI : 10.1073/pnas.1018525108

B. Sadlack, J. Lohler, H. Schorle, G. Klebb, H. Haber et al., Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells, European Journal of Immunology, vol.1, issue.11, pp.3053-3059, 1995.
DOI : 10.1002/eji.1830251111

S. Sakaguchi, Regulatory T Cells, Cell, vol.101, issue.5, pp.455-458, 2000.
DOI : 10.1016/S0092-8674(00)80856-9
URL : https://hal.archives-ouvertes.fr/hal-01358192

S. Sakaguchi, N. Sakaguchi, M. Asano, M. Itoh, and M. Toda, Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25) Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases, J. Immunol, vol.155, pp.1151-1164, 1995.

F. Sallusto, J. Geginat, and A. Lanzavecchia, : Function, Generation, and Maintenance, Annual Review of Immunology, vol.22, issue.1, pp.745-763, 2004.
DOI : 10.1146/annurev.immunol.22.012703.104702

H. Schorle, T. Holtschke, T. Hunig, A. Schimpl, and I. Horak, Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting, Nature, vol.352, issue.6336, pp.621-624, 1991.
DOI : 10.1038/352621a0

R. Setoguchi, S. Hori, T. Takahashi, and S. Sakaguchi, regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization, The Journal of Experimental Medicine, vol.136, issue.5, pp.723-735, 2005.
DOI : 10.1016/S1074-7613(00)80195-8

E. M. Shevach, Regulatory T Cells in Autoimmmunity, Annual Review of Immunology, vol.18, issue.1, pp.423-449, 2000.
DOI : 10.1146/annurev.immunol.18.1.423

E. M. Shevach, Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression, Immunity, vol.30, issue.5, pp.636-645, 2009.
DOI : 10.1016/j.immuni.2009.04.010

J. W. Snow, N. Abraham, M. C. Ma, B. G. Herndier, A. W. Pastuszak et al., Loss of Tolerance and Autoimmunity Affecting Multiple Organs in STAT5A/5B-Deficient Mice, The Journal of Immunology, vol.171, issue.10, pp.5042-5050, 2003.
DOI : 10.4049/jimmunol.171.10.5042

D. M. Soper, D. J. Kasprowicz, and S. F. Ziegler, IL-2R?? links IL-2R signaling with Foxp3 expression, European Journal of Immunology, vol.35, issue.7, pp.1817-1826, 2007.
DOI : 10.1002/eji.200737101

H. F. Stahl, T. Fauti, N. Ullrich, T. Bopp, J. Kubach et al., miR-155 Inhibition Sensitizes CD4+ Th Cells for TREG Mediated Suppression, PLoS ONE, vol.102, issue.9, 2009.
DOI : 10.1371/journal.pone.0007158.s006

C. D. Surh and J. Sprent, Homeostasis of Naive and Memory T Cells, Immunity, vol.29, issue.6, pp.848-862, 2008.
DOI : 10.1016/j.immuni.2008.11.002

H. Suzuki, T. M. Kundig, C. Furlonger, A. Wakeham, E. Timms et al., Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta, Science, vol.268, issue.5216, pp.1472-1476, 1995.
DOI : 10.1126/science.7770771

S. L. Swain, H. Hu, and G. Huston, Class II-Independent Generation of CD4 Memory T Cells from Effectors, Science, vol.286, issue.5443, pp.1381-1383, 1999.
DOI : 10.1126/science.286.5443.1381

K. Takeda, T. Tanaka, W. Shi, M. Matsumoto, M. Minami et al., Essential role of Stat6 in IL-4 signalling, Nature, vol.380, issue.6575, pp.627-630, 1996.
DOI : 10.1038/380627a0

J. T. Tan, E. Dudl, E. Leroy, R. Murray, J. Sprent et al., IL-7 is critical for homeostatic proliferation and survival of naive T cells, Proceedings of the National Academy of Sciences, vol.98, issue.15, pp.8732-8737, 2001.
DOI : 10.1073/pnas.161126098

C. Tanchot, F. A. Lemonnier, B. Perarnau, A. A. Freitas, and B. Rocha, Differential Requirements for Survival and Proliferation of CD8 Naïve or Memory T Cells, Science, vol.276, issue.5321, pp.2057-2062, 1997.
DOI : 10.1126/science.276.5321.2057

C. Tanchot and B. Rocha, The peripheral T cell repertoire: independent homeostatic regulation of virgin and activated CD8+ T cell pools, European Journal of Immunology, vol.66, issue.8, pp.2127-2136, 1995.
DOI : 10.1002/eji.1830250802

Q. Tang, J. Y. Adams, A. J. Tooley, M. Bi, B. T. Fife et al., Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice, Nature Immunology, vol.360, issue.1, pp.83-92, 2006.
DOI : 10.1038/ni1289

Q. Tang, J. Y. Adams, C. Penaranda, K. Melli, E. Piaggio et al., Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction, Immunity, vol.28, issue.5, pp.687-697, 2008.
DOI : 10.1016/j.immuni.2008.03.016

J. A. Todd, Etiology of Type 1 Diabetes, Immunity, vol.32, issue.4, pp.457-467, 2010.
DOI : 10.1016/j.immuni.2010.04.001

L. Vivien, C. Benoist, and D. Mathis, T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo, International Immunology, vol.13, issue.6, pp.763-768, 2001.
DOI : 10.1093/intimm/13.6.763

R. S. Wildin, F. Ramsdell, J. Peake, F. Faravelli, J. L. Casanova et al., X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy, Nature Genetics, vol.27, issue.1, pp.18-20, 2001.
DOI : 10.1038/83707

D. M. Willerford, J. Chen, J. A. Ferry, L. Davidson, A. Ma et al., Interleukin-2 receptor ?? chain regulates the size and content of the peripheral lymphoid compartment, Immunity, vol.3, issue.4, pp.521-530, 1995.
DOI : 10.1016/1074-7613(95)90180-9

M. A. Williams, A. J. Tyznik, and M. J. Bevan, Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells, Nature, vol.8, issue.7095, pp.890-893, 2006.
DOI : 10.1038/nature04790

K. Wing, Y. Onishi, P. Prieto-martin, T. Yamaguchi, M. Miyara et al., CTLA-4 Control over Foxp3+ Regulatory T Cell Function, Science, vol.322, issue.5899, pp.271-275, 2008.
DOI : 10.1126/science.1160062

M. Wolf, A. Schimpl, and T. Hunig, Control of T cell hyperactivation in IL-2-deficient mice by CD4+CD25- and CD4+CD25+ T cells: evidence for two distinct regulatory mechanisms, European Journal of Immunology, vol.159, issue.6, pp.1637-1645, 2001.
DOI : 10.1002/1521-4141(200106)31:6<1637::AID-IMMU1637>3.0.CO;2-T

Y. Wu, M. Borde, V. Heissmeyer, M. Feuerer, A. D. Lapan et al., FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT, Cell, vol.126, issue.2, pp.375-387, 2006.
DOI : 10.1016/j.cell.2006.05.042

Z. Yao, Y. Kanno, M. Kerenyi, G. Stephens, L. Durant et al., Nonredundant roles for Stat5a/b in directly regulating Foxp3, Blood, vol.109, issue.10, pp.4368-4375, 2007.
DOI : 10.1182/blood-2006-11-055756