Update in Cystic Fibrosis 2009, American Journal of Respiratory and Critical Care Medicine, vol.181, issue.6, pp.539-544, 2010. ,
DOI : 10.1164/rccm.200912-1943UP
The macrophage: Past, present and future, European Journal of Immunology, vol.18, issue.S1, pp.9-17, 2007. ,
DOI : 10.1002/eji.200737638
CFTR regulates phagosome acidification in macrophages and alters bactericidal activity, Nature Cell Biology, vol.167, issue.9, pp.933-944, 2006. ,
DOI : 10.1074/jbc.M400688200
Disease-causing Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator Determine the Functional Responses of Alveolar Macrophages, Journal of Biological Chemistry, vol.284, issue.51, pp.35926-35938, 2009. ,
DOI : 10.1074/jbc.M109.057372
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors, Nature Immunology, vol.1799, issue.5, pp.373-384, 2010. ,
DOI : 10.1126/science.1179050
Recognition of microorganisms and activation of the immune response, Nature, vol.158, issue.7164, pp.819-826, 2007. ,
DOI : 10.1038/nature06246
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens, Nature, vol.401, pp.811-815, 1999. ,
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors, Proceedings of the National Academy of Sciences, vol.97, issue.25, pp.13766-13771, 2000. ,
DOI : 10.1073/pnas.250476497
Regulation of Phagosome Maturation by Signals from Toll-Like Receptors, Science, vol.304, issue.5673, pp.1014-1018, 2004. ,
DOI : 10.1126/science.1096158
On regulation of phagosome maturation and antigen presentation, Nature Immunology, vol.173, issue.10, pp.1029-1035, 2006. ,
DOI : 10.1084/jem.20052433
Toll-like Receptors Induce a Phagocytic Gene Program through p38, The Journal of Experimental Medicine, vol.72, issue.1, pp.81-90, 2004. ,
DOI : 10.1111/j.1574-695X.2001.tb01586.x
Nonopsonic phagocytosis of Pseudomonas aeruginosa by macrophages and polymorphonuclear leukocytes requires the presence of the bacterial agellum, Infect Immun, vol.63, pp.4519-4523, 1995. ,
Pseudomonas aeruginosa activates caspase 1 through Ipaf, Proceedings of the National Academy of Sciences, vol.105, issue.7, pp.2562-2567, 2008. ,
DOI : 10.1073/pnas.0712183105
Critical role for Ipaf inPseudomonas aeruginosa-induced caspase-1 activation, European Journal of Immunology, vol.135, issue.11, pp.3030-3039, 2007. ,
DOI : 10.1002/eji.200737532
Type II Secretion System of Pseudomonas aeruginosa: In Vivo Evidence of a Significant Role in Death Due to Lung Infection, Journal of Infectious Diseases, vol.203, issue.10, pp.1369-1377, 2011. ,
DOI : 10.1093/infdis/jir045
Roles of Specific Amino Acids in the N Terminus of Pseudomonas aeruginosa Flagellin and of Flagellin Glycosylation in the Innate Immune Response, Infection and Immunity, vol.73, issue.12, pp.8237-8246, 2005. ,
DOI : 10.1128/IAI.73.12.8237-8246.2005
Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility, Nature Immunology, vol.4, issue.12, pp.1247-1253, 2003. ,
DOI : 10.1038/ni1011
Pseudomonas aeruginosa Evasion of Phagocytosis Is Mediated by Loss of Swimming Motility and Is Independent of Flagellum Expression, Infection and Immunity, vol.78, issue.7, pp.2937-2945, 2010. ,
DOI : 10.1128/IAI.00144-10
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome, Proceedings of the National Academy of Sciences, vol.107, issue.7, pp.3076-3080, 2010. ,
DOI : 10.1073/pnas.0913087107
Differential Requirements for NAIP5 in Activation of the NLRC4 Inflammasome, Infection and Immunity, vol.79, issue.4, pp.1606-1614, 2011. ,
DOI : 10.1128/IAI.01187-10
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1?? in salmonella-infected macrophages, Nature Immunology, vol.160, issue.6, pp.576-582, 2006. ,
DOI : 10.1038/ni1346
Regulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf, Journal of Biological Chemistry, vol.281, issue.46, pp.35217-35223, 2006. ,
DOI : 10.1074/jbc.M604933200
Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages, PLoS Pathogens, vol.202, issue.8, p.111, 2007. ,
DOI : 0022-1007(2005)202[1235:IOCWCP]2.0.CO;2
From The Cover: Phospholipases C and A2 control lysosome-mediated IL-1?? secretion: Implications for inflammatory processes, Proceedings of the National Academy of Sciences, vol.101, issue.26, pp.9745-9750, 2004. ,
DOI : 10.1073/pnas.0308558101
IL-1??: An endosomal exit, Proceedings of the National Academy of Sciences, vol.101, issue.28, pp.10241-10242, 2004. ,
DOI : 10.1073/pnas.0403971101
TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage, Mucosal Immunology, vol.67, issue.1, pp.102-111, 2011. ,
DOI : 10.1053/j.gastro.2005.09.017
Endolysosomal proteases and their inhibitors in immunity, Nature Reviews Immunology, vol.135, issue.12, pp.871-882, 2009. ,
DOI : 10.1038/nri2671
Critical Role for Asparagine Endopeptidase in??Endocytic Toll-like Receptor Signaling in Dendritic Cells, Immunity, vol.31, issue.5, pp.737-748, 2009. ,
DOI : 10.1016/j.immuni.2009.09.013
Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria, Proceedings of the National Academy of Sciences, vol.103, issue.33, pp.12487-12492, 2006. ,
DOI : 10.1073/pnas.0605200103
URL : https://hal.archives-ouvertes.fr/hal-00165595
TLRs 2 and 4 Are Not Involved in Hypersusceptibility to Acute Pseudomonas aeruginosa Lung Infections, The Journal of Immunology, vol.175, issue.6, pp.3927-3934, 2005. ,
DOI : 10.4049/jimmunol.175.6.3927
mediated by the IPAF/NLRC4 inflammasome, The Journal of Experimental Medicine, vol.67, issue.13, pp.3235-3245, 2007. ,
DOI : 10.1016/S0378-1119(98)00130-9