Abstract : The pyrazole nucleus has recently become a recurrent scaffold in the research fields of CropScience and oncology. We report here the preparation of an array of 4- and 5-iodinated pyrazole derivatives, such as 4-iodo-3-trifluoromethylpyrazole or ethyl 5-iodo-4-carboxy-3-trifluoromethylpyrazoles. This work provide access to many new pyrazole derivative, including 11 original out of 16 iodinated building blocks, thus opening accesses to new chemical entities featuring a pyrazole nucleus.
https://hal-pasteur.archives-ouvertes.fr/pasteur-00629132
Contributor : Yves Janin <>
Submitted on : Wednesday, October 5, 2011 - 10:32:39 AM Last modification on : Wednesday, November 11, 2020 - 8:52:02 AM