Acta Cryst, pp.213-221, 2010. ,
X-ray Diffraction Screening, Crystal Growth & Design, vol.11, issue.4, pp.916-923, 2011. ,
DOI : 10.1021/cg101375j
From fragment to clinical candidate???a historical perspective, Drug Discovery Today, vol.14, issue.13-14, pp.668-675, 2009. ,
DOI : 10.1016/j.drudis.2009.04.007
To automate or not to automate: this is the question, Journal of Structural and Functional Genomics, vol.61, issue.Suppl, pp.211-221, 2010. ,
DOI : 10.1007/s10969-010-9092-9
Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid, The EMBO Journal, vol.19, issue.11, pp.2592-2601, 2000. ,
DOI : 10.1093/emboj/19.11.2592
Acta Cryst, pp.2126-2132, 2004. ,
Automated Analysis of Vapor Diffusion Crystallization Drops with an X-Ray Beam, Structure, vol.12, issue.7, pp.1219-1225, 2004. ,
DOI : 10.1016/j.str.2004.04.019
High-throughput crystallography for structural genomics???, Current Opinion in Structural Biology, vol.19, issue.5, pp.573-584, 2009. ,
DOI : 10.1016/j.sbi.2009.08.002
Crystal structure of human cyclophilin D in complex with its inhibitor, cyclosporin A at 0.96-?? resolution, Proteins: Structure, Function, and Bioinformatics, vol.8, issue.Part 1, pp.1635-1639, 2008. ,
DOI : 10.1002/prot.21855
Activation of RXR???PPAR heterodimers by organotin environmental endocrine disruptors, EMBO reports, vol.10, issue.4, pp.367-373, 2009. ,
DOI : 10.1074/jbc.M409302200
URL : https://hal.archives-ouvertes.fr/inserm-00375675
Acta Cryst, pp.48-57, 2006. ,
Structural biology in fragment-based drug design, Current Opinion in Structural Biology, vol.20, issue.4, pp.497-507, 2010. ,
DOI : 10.1016/j.sbi.2010.04.003
@TOME-2: a new pipeline for comparative modeling of protein-ligand complexes, Nucleic Acids Research, vol.37, issue.Web Server, pp.485-491, 2009. ,
DOI : 10.1093/nar/gkp368
The RCSB Protein Data Bank: redesigned web site and web services, Nucleic Acids Research, vol.39, issue.Database, pp.392-401, 2011. ,
DOI : 10.1093/nar/gkq1021
Recent progress in fragment-based lead discovery, Current Opinion in Pharmacology, vol.9, issue.5, pp.615-621, 2009. ,
DOI : 10.1016/j.coph.2009.04.009
Acta Cryst, pp.22-25, 2010. ,
Structural basis of inhibitor selectivity in MAP kinases, Structure, vol.6, issue.9, pp.1117-1128, 1998. ,
DOI : 10.1016/S0969-2126(98)00113-0
Acta Cryst, pp.235-242, 2011. ,
Atomic structure of the MAP kinase ERK2 at 2.3 ?? resolution, Nature, vol.367, issue.6465, pp.704-711, 1994. ,
DOI : 10.1038/367704a0