Skip to Main content Skip to Navigation
Journal articles

CrAsH-quantum dot nanohybrids for smart targeting of proteins.

Abstract : Smart nanohybrids were prepared by conjugation of CrAsH to hydrosoluble and biocompatible quantum dots (QDs). The resulting probes were shown to bind efficiently and selectively to Cys-tagged proteins. The interaction with the protein was detected by an increase of the fluorescence emission of CrAsH. While the latter faded rapidly under continuous excitation, emission of the QD remained unaffected. The persistent fluorescence of the QD should thus allow extended monitoring of the target protein.
Document type :
Journal articles
Complete list of metadatas

https://hal-pasteur.archives-ouvertes.fr/pasteur-00457766
Contributor : Mireille Gau <>
Submitted on : Thursday, February 18, 2010 - 2:04:00 PM
Last modification on : Tuesday, October 6, 2020 - 5:16:01 PM

Links full text

Identifiers

Citation

Emilie Genin, Olivier Carion, Benoit Mahler, Benoit Dubertret, Nathalie Arhel, et al.. CrAsH-quantum dot nanohybrids for smart targeting of proteins.. Journal of the American Chemical Society, American Chemical Society, 2008, 130 (27), pp.8596-7. ⟨10.1021/ja802987q⟩. ⟨pasteur-00457766⟩

Share

Metrics

Record views

299