New insights into prevalence, genetic diversity, and proviral load of human T-cell leukemia virus types 1 and 2 in pregnant women in Gabon in equatorial central Africa. - Archive ouverte HAL Access content directly
Journal Articles Journal of Clinical Microbiology Year : 2008

New insights into prevalence, genetic diversity, and proviral load of human T-cell leukemia virus types 1 and 2 in pregnant women in Gabon in equatorial central Africa.

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Abstract

Human T-cell leukemia virus type 1 (HTLV-1) is highly endemic in areas of central Africa; mother-to-child transmission and sexual transmission are considered to be the predominant routes. To determine the prevalence and subtypes of HTLV-1/2 in pregnant women in Gabon, we conducted an epidemiological survey in the five main cities of the country. In 907 samples, the HTLV-1 seroprevalence was 2.1%, which is lower than that previously reported. Only one case of HTLV-2 infection was found. The HTLV-1 seroprevalence increased with age and differed between regions (P

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pasteur-00363876 , version 1 (24-02-2009)

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Sonia Lekana-Douki Etenna, Mélanie Caron, Guillaume Besson, Maria Makuwa, Antoine Gessain, et al.. New insights into prevalence, genetic diversity, and proviral load of human T-cell leukemia virus types 1 and 2 in pregnant women in Gabon in equatorial central Africa.. Journal of Clinical Microbiology, 2008, 46 (11), pp.3607-14. ⟨10.1128/JCM.01249-08⟩. ⟨pasteur-00363876⟩
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