J. A. Owen, M. Allouche, and P. C. Doherty, Limiting dilution analysis of the specificity of influenza-immune cytotoxic T cells, Cellular Immunology, vol.67, issue.1, pp.49-59, 1982.
DOI : 10.1016/0008-8749(82)90198-8

Z. Tabi, F. Lynch, K. Ceredig, J. E. Allan, and P. C. Doherty, Virus-specific memory T cells are Pgp-1+ and can be selectively activated with phorbol ester and calcium lonophore, Cellular Immunology, vol.113, issue.2, pp.268-277, 1988.
DOI : 10.1016/0008-8749(88)90026-3

S. Hou and P. Doherty, Partioning of responder CD8 + T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype, J, 1993.

F. J. Kos and A. Mullbacher, Ib2 independent activity of II,-7 in the generation of secondary antigen-specific cytotoxic T cell responses "in vitro, J. Immunol, vol.150, pp.387-393, 1993.

P. Beverley, Is T-cell memory maintained by crossreactive stimulation?, Immunology Today, vol.11, pp.203-205, 1990.
DOI : 10.1016/0167-5699(90)90083-L

B. Kocha and H. Yon-boehmer, Peripheral selection of the T cell repertoire, Science (Wash. DC), vol.251, pp.1225-1228, 1991.

B. Rocha, C. Tanchot, and H. Yon-boehmer, Clonal anergy blocks in vivo growth of mature T cells and can be reversed in the absence of antigen, Journal of Experimental Medicine, vol.177, issue.5, pp.1517-1521, 1993.
DOI : 10.1084/jem.177.5.1517

H. Von-boehmer and K. Hafen, The life span of naive alpha/beta T cells in secondary lymphoid organs, Journal of Experimental Medicine, vol.177, issue.4, pp.891-896, 1993.
DOI : 10.1084/jem.177.4.891

C. A. Michie, A. Mclean, C. Alcock, and P. C. Beverley, Lifespan of human lymphocyte subsets defined by CD45 isoforms, Nature, vol.360, issue.6401, pp.242-244, 1992.
DOI : 10.1038/360264a0

J. Kirberg, L. Bruno, and H. Yon-boehmer, CD4+8??? help prevents rapid deletion of CD8+ cells after a transient response to antigen, European Journal of Immunology, vol.4, issue.8, pp.1963-1967, 1993.
DOI : 10.1002/eji.1830230835

D. A. Carlow, S. J. Teh, N. S. Van-oers, K. G. Miller, and H. Teh, T cells, International Immunology, vol.4, issue.5, pp.599-610, 1992.
DOI : 10.1093/intimm/4.5.599

J. Colic, P. Truffa-bachi, and A. A. Freitas, Secondary antibody responses to thymus-independent antigens. Decline and life-span of memory, Eur. J. Immunol, vol.18, pp.1307-1314, 1988.

D. Gray and P. Matzinger, T cell memory is short-lived in the absence of antigen, Journal of Experimental Medicine, vol.174, issue.5, pp.969-974, 1991.
DOI : 10.1084/jem.174.5.969

E. B. Bell and S. M. Sparshott, Interconversion of CD45R subsets of CD4 T cells in vivo, Nature, vol.348, issue.6297, pp.163-166, 1990.
DOI : 10.1038/348163a0

R. Ahmed, Immunological memory against viruses, Semin. Immunol, vol.4, pp.105-109, 1992.

M. C. Eichelberg, M. Wang, W. Allan, R. G. Webster, and P. Doherty, Influenza virus KNA in the lung and lymphoid tissue ofimmunologically intact and CD4-depleted mice, 1991.

D. Moskophidis, F. Lechner, H. Pitcher, and R. M. , Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells, Nature, vol.362, issue.6422, pp.758-761, 1993.
DOI : 10.1038/362758a0

S. Webb, C. Morris, and J. Sprent, Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity, Cell, vol.63, issue.6, pp.1249-1256, 1990.
DOI : 10.1016/0092-8674(90)90420-J

H. K. Macdonald, S. Baschieri, and K. K. Lees, Clonal expansion precedes anergy and death of V??8+ peripheral T cells responding to staphylococcal enterotoxin Bin vivo, European Journal of Immunology, vol.17, issue.8, pp.1963-1966, 1991.
DOI : 10.1002/eji.1830210827

S. Guerder and P. Matzinger, A fail-safe mechanism for maintaining self-tolerance, Journal of Experimental Medicine, vol.176, issue.2, pp.553-564, 1992.
DOI : 10.1084/jem.176.2.553

E. J. Fuchs and P. Matzinger, B cells turn off virgin but not memory T cells, Science, vol.258, issue.5085, pp.1156-1159, 1992.
DOI : 10.1126/science.1439825

P. Kisielow, H. Bluthman, U. D. Staerz, M. Steinmetz, and H. Von-boehmer, Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes, Nature, vol.333, issue.6175, pp.742-746, 1988.
DOI : 10.1038/333742a0

H. S. Teh, P. Kisielow, B. Scott, H. Kishi, Y. Uematsu et al., Thymic major histocompatibility complex antigens and the ???? T-cell receptor determine the CD4/CD8 phenotype of T cells, Thymic MHC antigens and the c~ TCK determine the CD4/CD8 phenotype of mature T cells, pp.229-233, 1988.
DOI : 10.1038/335229a0

D. Guy-grand, N. Cerf-bensussan, B. Malissen, M. Malissen-seris, C. Briottet et al., Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation, Journal of Experimental Medicine, vol.173, issue.2, pp.471-481, 1991.
DOI : 10.1084/jem.173.2.471

B. Rocha, N. Dautigny, and P. Pereira, Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratiosin vivo, European Journal of Immunology, vol.328, issue.5, pp.905-911, 1989.
DOI : 10.1002/eji.1830190518

K. L. Coffman and I. L. Weissman, A monoclonal antibody that recognizes B cells and B cell precursors in mice, Journal of Experimental Medicine, vol.153, issue.2, 1981.
DOI : 10.1084/jem.153.2.269

R. Schiippel, J. Wilke, and E. Weiuer, Monoclonal antiallotype antibody towards BALB/c IgM. Analysis of specificity and site of a V-C crossover in recombinant strain, 1987.

S. I. Nishikawa, Y. Sasaki, T. Kina, T. Amagai, and Y. Katsura, A monoclonal antibody against Igh6-4 determinant, Immunogenetics, vol.133, issue.2, pp.137-139, 1986.
DOI : 10.1007/BF00377976

P. Koopman, J. Gubbay, N. Vivian, P. Goodfellow, and R. Lovell-badge, Male development of chromosomally female mice transgenic for Sry, Nature, vol.351, issue.6322, pp.117-121, 1991.
DOI : 10.1038/351117a0

H. Von-boehmer, J. Kirberg, and B. Kocha, An unusual lineage of alpha/beta T cells that contains autoreactive cells, Journal of Experimental Medicine, vol.174, issue.5, pp.1001-1008, 1991.
DOI : 10.1084/jem.174.5.1001

A. A. Freitas and M. De-sousa, Control mechanisms of lymphocyte traffic. Modification of the traffic of51 Cr-Labeled mouse lymph node cells by treatment with plant lectins in intact and splenectomized hosts, European Journal of Immunology, vol.141, issue.12, pp.831-838, 1975.
DOI : 10.1002/eji.1830051207

S. Oehen, H. Waldner, T. Kundig, H. Hengartner, and K. M. , Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen, Journal of Experimental Medicine, vol.176, issue.5, pp.1273-1282, 1992.
DOI : 10.1084/jem.176.5.1273

L. Hayflick, The limited in vitro lifetime of human diploid cell strains, Experimental Cell Research, vol.37, issue.3, pp.614-636, 1965.
DOI : 10.1016/0014-4827(65)90211-9

M. Huesmann, P. Scott, H. Kisielow, and . Von-boehmer, Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice, Cell, vol.66, issue.3, pp.533-540, 1991.
DOI : 10.1016/0092-8674(81)90016-7

P. R. Walden and H. N. Eisen, Cognate peptides induce self-destruction of CD8+ cytolytic T lymphocytes., Proc. Natl. Acad. Sci. USA, pp.9015-9019, 1990.
DOI : 10.1073/pnas.87.22.9015

A. A. Freitas and B. Kocha, Lymphocyte lifespans: homeostasis, selection and competition, Immunology Today, vol.14, issue.1, pp.25-29, 1993.
DOI : 10.1016/0167-5699(93)90320-K