AIDS: decline and fall of immune surveillance?

Mark B. Feinberg (1) , Angela R. Mclean (2)

1 Office of AIDS research
2 Dynamiques Lymphocytaires

Recent observations cast doubt on the view that cytotoxic T cells play a key role in keeping HIV-1 infection in check, and that it is the decline in this mechanism of immune surveillance that permits progression to AIDS.

Domains: Life Sciences [q-bio]; Immunology

Mark B. Feinberg, Angela R. Mclean. AIDS: decline and fall of immune surveillance?. Current Biology - CB, 1997, 7 (3), pp.R136-40. ⟨10.1016/S0960-9822(97)70072-1⟩. ⟨pasteur-00327548⟩