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Journal Articles Current Opinion in Immunology Year : 1999

Peripheral T cell survival.


T cell survival in the periphery is an active process, depending on continuous TCR engagement by peptide-MHC complexes and/or response to environmental cytokines. Naive T cells require interactions with the MHC restricting element. The survival requirements of memory T cells are as yet insufficiently characterized, but MHC-restricted interactions are not necessary.

Dates and versions

pasteur-00327522 , version 1 (08-10-2008)



A. A. Freitas, B. Rocha. Peripheral T cell survival.. Current Opinion in Immunology, 1999, 11 (2), pp.152-6. ⟨10.1016/S0952-7915(99)80026-0⟩. ⟨pasteur-00327522⟩
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