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. Antibody, Blots were then stripped and reprobed with an antibody recognizing all forms of 456

. Signaling, Inhibition of PV-induced ASK1 466 phosphorylation by the PI3K/Akt pathway inhibitor wortmannin Cells were uninfected or 467 infected with PV in the presence or absence of wortmannin (100 nM) ASK1 phosphorylation 468 was analyzed (30 min p.i.) in whole-cell lysates by Western blotting with a specific anti- 469 phospho (Ser83)-ASK1 antibody. Blots were then stripped and reprobed with an antibody 470 recognizing all forms of ASK1, to confirm equal protein loading, p.473