Apoptosis: Programmed cell death at a molecular level, Seminars in Arthritis and Rheumatism, vol.32, issue.6, pp.345-369, 2003. ,
DOI : 10.1053/sarh.2003.50005
The Hallmarks of Cancer, Cell, vol.100, issue.1, pp.57-70, 2000. ,
DOI : 10.1016/S0092-8674(00)81683-9
Apoptosis in the pathogenesis and treatment of disease, Science, vol.267, issue.5203, pp.1456-1462, 1995. ,
DOI : 10.1126/science.7878464
Anticancer therapy targeting the apoptotic pathway, The Lancet Oncology, vol.4, issue.12, pp.721-729, 2003. ,
DOI : 10.1016/S1470-2045(03)01277-4
Prospective strategies to enforce selectively cell death in cancer cells, Oncogene, vol.23, issue.16, pp.2967-2975, 2004. ,
DOI : 10.1038/sj.onc.1207520
Two Distinct Pathways Leading to Nuclear Apoptosis, The Journal of Experimental Medicine, vol.351, issue.4, pp.571-580, 2000. ,
DOI : 10.1016/S0960-9822(99)80240-1
URL : https://hal.archives-ouvertes.fr/hal-00315087
Programmed cell death: many ways for cells to die decently, Annals of Medicine, vol.20, issue.6, pp.480-488, 2002. ,
DOI : 10.1038/sj.cdd.4400859
Multiple cell death pathways as regulators of tumour initiation and progression, Oncogene, vol.23, issue.16, pp.2746-2756, 2004. ,
DOI : 10.1038/sj.onc.1207513
Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space, The EMBO Journal, vol.15, issue.7, pp.1375-1386, 2005. ,
DOI : 10.1038/sj.emboj.7600614
Mitochondrial effectors in caspase-independent cell death, FEBS Letters, vol.270, issue.1-3, pp.14-20, 2004. ,
DOI : 10.1016/S0014-5793(03)01464-9
URL : https://hal.archives-ouvertes.fr/pasteur-00193650
NADH Oxidase Activity of Mitochondrial Apoptosis-inducing Factor, Journal of Biological Chemistry, vol.276, issue.19, pp.16391-16398, 2001. ,
DOI : 10.1074/jbc.M010498200
AIF deficiency compromises oxidative phosphorylation, The EMBO Journal, vol.18, issue.23, pp.4679-4689, 2004. ,
DOI : 10.1074/jbc.M308143200
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC533047
The harlequin mouse mutation downregulates apoptosis-inducing factor, Nature, vol.58, issue.6905, pp.367-374, 2002. ,
DOI : 10.1038/39601
Calpain I Induces Cleavage and Release of Apoptosis-inducing Factor from Isolated Mitochondria, Journal of Biological Chemistry, vol.280, issue.8, pp.6447-6454, 2005. ,
DOI : 10.1074/jbc.M413269200
Caspase-Independent Cell Death by Arsenic Trioxide in Human Cervical Cancer Cells: Reactive Oxygen Species-Mediated Poly(ADP-ribose) Polymerase-1 Activation Signals Apoptosis-Inducing Factor Release from Mitochondria, Cancer Research, vol.64, issue.24, pp.8960-8967, 2004. ,
DOI : 10.1158/0008-5472.CAN-04-1830
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death, The Journal of Cell Biology, vol.17, issue.3, pp.507-517, 2002. ,
DOI : 10.1038/sj.bmt.1701121
Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells, Cell Research, vol.63, issue.3, pp.188-196, 2004. ,
DOI : 10.1002/ijc.10822
Sulindac activates nuclear translocation of AIF, DFF40 and endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells, Life Sciences, vol.77, issue.16, pp.2059-2070, 2005. ,
DOI : 10.1016/j.lfs.2005.04.021
Geldanamycin induces mitotic catastrophe and subsequent apoptosis in human glioma cells, Journal of Cellular Physiology, vol.151, issue.31, pp.374-384, 2004. ,
DOI : 10.1002/jcp.20090
Targeting PBR by Hexaminolevulinate-Mediated Photodynamic Therapy Induces Apoptosis through Translocation of Apoptosis-Inducing Factor in Human Leukemia Cells, Cancer Research, vol.65, issue.23, pp.11051-11060, 2005. ,
DOI : 10.1158/0008-5472.CAN-05-0510
Apoptosis-Inducing Factor Substitutes for Caspase Executioners in NMDA-Triggered Excitotoxic Neuronal Death, Journal of Neuroscience, vol.24, issue.48, pp.10963-10973, 2004. ,
DOI : 10.1523/JNEUROSCI.3461-04.2004
Apoptosis-inducing factor determines the chemoresistance of non-small-cell lung carcinomas, Oncogene, vol.23, issue.37, pp.6282-6291, 2004. ,
DOI : 10.1038/sj.onc.1207835
AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cells, The EMBO Journal, vol.19, issue.15, pp.2815-2826, 2005. ,
DOI : 10.1074/jbc.M308143200
Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor, The FASEB Journal, vol.15, issue.3, pp.758-767, 2001. ,
DOI : 10.1096/fj.00-0388com
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease, Journal of Experimental Medicine, vol.184, issue.4, pp.1331-1341, 1996. ,
DOI : 10.1084/jem.184.4.1331
Heat-shock protein 70 antagonizes apoptosis-inducing factor, Nature Cell Biology, vol.3, issue.9, pp.839-843, 2001. ,
DOI : 10.1038/ncb0901-839
Regulation of Human p53 Activity and Cell Localization by Alternative Splicing, Molecular and Cellular Biology, vol.24, issue.18, pp.7987-7997, 2004. ,
DOI : 10.1128/MCB.24.18.7987-7997.2004
Regulation of Apoptosis by Alternative Pre-mRNA Splicing, Molecular Cell, vol.19, issue.1, pp.1-13, 2005. ,
DOI : 10.1016/j.molcel.2005.05.026
Alternative Splicing and Programmed Cell Death, Experimental Biology and Medicine, vol.220, issue.2, pp.64-72, 1999. ,
DOI : 10.3181/00379727-220-44346
Repetitive Elements in the 5??? Untranslated Region of a Human Zinc-Finger Gene Modulate Transcription and Translation Efficiency, Genomics, vol.76, issue.1-3, pp.110-116, 2001. ,
DOI : 10.1006/geno.2001.6604
The crystal structure of the mouse apoptosis-inducing factor AIF, Nature Structural Biology, vol.9, issue.6, pp.442-446, 2002. ,
DOI : 10.1038/nsb793
Role of the Heat Shock Response and Molecular Chaperones in Oncogenesis and Cell Death, Journal of the National Cancer Institute, vol.92, issue.19, pp.1564-1572, 2000. ,
DOI : 10.1093/jnci/92.19.1564
AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis, Oncogene, vol.23, issue.8, pp.1514-1521, 2004. ,
DOI : 10.1038/sj.onc.1207279
Mechanisms of AIF-Mediated Apoptotic DNA Degradation in Caenorhabditis elegans, Science, vol.298, issue.5598, pp.1587-1592, 2002. ,
DOI : 10.1126/science.1076194
Apoptosis and metastasis: increased apoptosis resistance of metastatic cancer cells is associated with the profound deficiency of apoptosis execution mechanisms, Cancer Letters, vol.115, issue.2, pp.185-193, 1997. ,
DOI : 10.1016/S0304-3835(97)04738-1
Gene expression profiling predicts clinical outcome of prostate cancer, Journal of Clinical Investigation, vol.113, issue.6, pp.913-923, 2004. ,
DOI : 10.1172/JCI20032DS1
A Gene Expression Signature for Relapse of Primary Wilms Tumors, Cancer Research, vol.65, issue.7, pp.2592-2601, 2005. ,
DOI : 10.1158/0008-5472.CAN-04-1532
Total cell lysates from HeLa cells treated with STS for 8 h or transfected with pcDNA3-AIF (AIF) or pcDNA3-AIFsh (AIFsh) were obtained at different times and probed for the detection of AIF, caspase3, or ICAD. Equal loading was confirmed by actin detection. The precursor forms of caspase-3 and ICAD were cleaved only in HeLa cells treated by STS but not in cells ,