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Journal articles
Pulsed-field gel electrophoresis analysis of Bordetella pertussis populations in various European countries with different vaccine policies.
Valérie Caro
1
Elisabeth Njamkepo
1
Shirley C M van Amersfoorth
2
Frits R Mooi
2
Abdolreza Advani
3
Hans O Hallander
3
Qiushui He
4
Jussi Mertsola
4
Marion Riffelmann
5
Carola Vahrenholz
5
Carl H W von König
5
Nicole Guiso
1
Valérie Caro 1
Author
Elisabeth Njamkepo 1
Author IdHAL : elisabeth-njamkepo ORCID : https://orcid.org/0000-0001-6791-6003
Shirley C M van Amersfoorth 2
Author
Frits R Mooi 2
Author
Marion Riffelmann 5
Author
Carola Vahrenholz 5
Author
Carl H W von König 5
Author
Nicole Guiso 1
Author
1
Prévention et Thérapie Moléculaires des Maladies Infectieuses Humaines (25 rue du Docteur Roux F-75724 Paris Cedex 15 - France)
- Institut Pasteur [Paris] (25-28, rue du docteur Roux, 75724 Paris cedex 15 - France)
- CNRS - Centre National de la Recherche Scientifique : URA3012 (France)
2
Laboratory for vaccine preventable diseases (Bilthoven - Netherlands)
- RIVM - National Institute for Public Health and the Environment [Bilthoven] (Antonie van Leeuwenhoeklaan 9, 3721 MA, Bilthoven / PO Box 1, 3720 BA Bilthoven - Netherlands)
3
Swedish Institute for Infectious Disease Control (S-171 82 Solna, Sweden - France)
4
The Pertussis Reference Laboratory (Turku - Finland)
- University of Turku (20014 Turun yliopisto, Finland - Finland)
- National Public Health Institute (France)
Abstract : The increasing incidence of pertussis in a number of countries, despite good vaccination coverage, is a cause for concern. We used pulsed-field gel electrophoresis (PFGE) typing to examine the genetic diversity of 101 clinical isolates of Bordetella pertussis, recovered during 1999-2001, and circulating in five different European countries to evaluate temporal and geographical distribution. This DNA fingerprinting approach seems to be a more discriminative epidemiological tool than sequencing of individual genes. Despite differences in vaccination policies in the five countries, these European isolates were found to be very similar and fell into the same major PFGE profile groups, with a predominance of one profile group. There was no evidence of geographic clustering, except that one new profile subgroup was predominantly found in one country. This study provides a baseline for continued surveillance of the B. pertussis population in Europe.
Document type :
Journal articles
Complete list of metadatas
https://hal-pasteur.archives-ouvertes.fr/pasteur-00169334
Contributor : Laurence Langlais <>
Submitted on : Monday, September 3, 2007 - 2:06:54 PM
Last modification on : Thursday, June 18, 2020 - 6:14:02 PM
Contributor : Laurence Langlais <>
Submitted on : Monday, September 3, 2007 - 2:06:54 PM
Last modification on : Thursday, June 18, 2020 - 6:14:02 PM
Identifiers
- HAL Id : pasteur-00169334, version 1
- DOI : 10.1016/j.micinf.2005.04.005
- PUBMED : 15994109
Citation
Valérie Caro, Elisabeth Njamkepo, Shirley C M van Amersfoorth, Frits R Mooi, Abdolreza Advani, et al.. Pulsed-field gel electrophoresis analysis of Bordetella pertussis populations in various European countries with different vaccine policies.. Microbes and Infection, Elsevier, 2005, 7 (7-8), pp.976-82. ⟨10.1016/j.micinf.2005.04.005⟩. ⟨pasteur-00169334⟩