Skip to Main content Skip to Navigation
Journal articles

New fluorescent and photoactivable analogs acting on nucleotide binding enzymes

Abstract : We describe a seven-step synthesis of 8-azido-3′-O-anthraniloyl-2′dADP and 2′dATP from 8-azido-2′deoxyadenosine. These compounds can be used as fluorescent and photoactivable probes for the nucleotide-binding site of kinases or cyclases. These two analogs of ADP and ATP were synthesized and used as fluorescent and photoactivable probes for the nucleotide binding site of bacterial adenylate cyclase.
Document type :
Journal articles
Complete list of metadatas

https://hal-pasteur.archives-ouvertes.fr/pasteur-00167097
Contributor : Hélène Munier-Lehmann <>
Submitted on : Tuesday, August 14, 2007 - 4:35:46 PM
Last modification on : Tuesday, June 9, 2020 - 12:36:05 PM

Links full text

Identifiers

Collections

Citation

Robert S. Sarfati, Abdelkader Namane, Hélène Munier, Octavian Barzu. New fluorescent and photoactivable analogs acting on nucleotide binding enzymes. Tetrahedron Letters, Elsevier, 1991, 32 (36), pp.4699-4702. ⟨10.1016/S0040-4039(00)92285-8⟩. ⟨pasteur-00167097⟩

Share

Metrics

Record views

240