FKBP-rapamycin inhibits a cyclin-dependent kinase activity and a cyclin D1-Cdk association in early G1 of an osteosarcoma cell line, J. Biol. Chem, vol.268, pp.22825-22829, 1993. ,
Alternative splicing: multiple control mechanisms and involvement in human disease, Trends in Genetics, vol.18, issue.4, pp.186-193, 2002. ,
DOI : 10.1016/S0168-9525(01)02626-9
LISTENING TO SILENCE AND UNDERSTANDING NONSENSE: EXONIC MUTATIONS THAT AFFECT SPLICING, Nature Reviews Genetics, vol.3, issue.4, pp.285-298, 2002. ,
DOI : 10.1038/nrg775
Cyclosporin A Induces Proliferation in Human Gingival Fibroblasts via Induction of Transforming Growth Factor-??1, Journal of Periodontology, vol.74, issue.11, pp.1625-1633, 2003. ,
DOI : 10.1902/jop.2003.74.11.1625
Generic Signals and Specific Outcomes, Cell, vol.96, issue.5, pp.611-614, 1999. ,
DOI : 10.1016/S0092-8674(00)80571-1
URL : http://doi.org/10.1016/s0092-8674(00)80571-1
Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation, Science, vol.246, issue.4937, pp.1617-1620, 1989. ,
DOI : 10.1126/science.2595372
Immunophilins in protein folding and immunosuppression, FASEB J, vol.8, pp.391-400, 1994. ,
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A., Proceedings of the National Academy of Sciences, vol.89, issue.9, pp.3686-3690, 1992. ,
DOI : 10.1073/pnas.89.9.3686
The superfamily of arginine/serine-rich splicing factors, RNA, vol.1, pp.663-680, 1995. ,
Synaptotagmin-like Protein 1-3: A Novel Family of C-Terminal-Type Tandem C2 Proteins, Biochemical and Biophysical Research Communications, vol.281, issue.5, pp.1226-1233, 2001. ,
DOI : 10.1006/bbrc.2001.4512
Novel Splicing Isoforms of Synaptotagmin-like Proteins 2 and 3: Identification of the Slp Homology Domain, Biochemical and Biophysical Research Communications, vol.283, issue.2, pp.513-519, 2001. ,
DOI : 10.1006/bbrc.2001.4803
Alternative splicing in disease and therapy, Nature Biotechnology, vol.22, issue.5, pp.535-546, 2004. ,
DOI : 10.1038/nbt964
Sorting out the complexity of SR protein functions, RNA, vol.6, issue.9, pp.1197-1211, 2000. ,
DOI : 10.1017/S1355838200000960
A cyclophilin functions in pre-mRNA splicing, The EMBO Journal, vol.5, issue.3, pp.470-480, 2002. ,
DOI : 10.1093/emboj/21.3.470
Analysis of the AP-1 sites in the IL-2 promoter, J. Immunol, vol.148, pp.1240-1250, 1992. ,
Pre-mRNA Splicing, Molecular Cell, vol.12, issue.1, pp.5-14, 2003. ,
DOI : 10.1016/S1097-2765(03)00270-3
REGULATION OF NEW DNA SYNTHESIS IN MAMMALIAN CELLS BY CYCLOSPORINE, Transplantation, vol.57, issue.4, pp.577-582, 1994. ,
DOI : 10.1097/00007890-199402000-00018
Manipulating Immune Responses with Immunosuppressive Agents that Target NFAT, Immunity, vol.12, issue.4, pp.359-372, 2000. ,
DOI : 10.1016/S1074-7613(00)80188-0
Crystal structures of human calcineurin and the human FKBP12???FK506???calcineurin complex, Nature, vol.378, issue.6557, pp.641-644, 1995. ,
DOI : 10.1038/378641a0
Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes, Nature Cell Biology, vol.5, issue.12, pp.1195-1203, 2004. ,
DOI : 10.1042/BJ20040096
A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes, Nat. Genet, vol.27, pp.55-58, 2001. ,
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes, Cell, vol.66, issue.4, pp.807-815, 1991. ,
DOI : 10.1016/0092-8674(91)90124-H
Characterization of a Gene Encoding Two Isoforms of a Mitochondrial Protein Up-regulated by Cyclosporin A in Activated T Cells, Journal of Biological Chemistry, vol.279, issue.11, pp.10556-10563, 2004. ,
DOI : 10.1074/jbc.M313770200
URL : https://hal.archives-ouvertes.fr/pasteur-00327345
INCREASED PROTEIN SYNTHESIS AFTER T CELL ACTIVATION IN PRESENCE OF CYCLOSPORIN A1, Transplantation, vol.70, issue.2, pp.340-348, 2000. ,
DOI : 10.1097/00007890-200007270-00019
Cyclosporin A therapy differently affects immunological-relevant gene expression following immunization, Immunology Letters, vol.84, issue.2, pp.137-143, 2002. ,
DOI : 10.1016/S0165-2478(02)00157-8
URL : https://hal.archives-ouvertes.fr/pasteur-00327455
New Aspects of Cyclosporin A Mode of Action: from Gene Silencing to Gene Up-Regulation, Mini-Reviews in Medicinal Chemistry, vol.3, issue.3, pp.207-216, 2003. ,
DOI : 10.2174/1389557033488150
URL : https://hal.archives-ouvertes.fr/pasteur-00327428
X-ray structure of a cyclophilin B/cyclosporin complex: comparison with cyclophilin A and delineation of its calcineurin-binding domain., Proceedings of the National Academy of Sciences, vol.91, issue.11, pp.5183-5186, 1994. ,
DOI : 10.1073/pnas.91.11.5183
A genomic view of alternative splicing, Nature Genetics, vol.30, issue.1, pp.13-19, 2002. ,
DOI : 10.1038/ng0102-13
Genome-wide detection of alternative splicing in expressed sequences of human genes, Nucleic Acids Research, vol.29, issue.13, pp.2850-2859, 2001. ,
DOI : 10.1093/nar/29.13.2850
Regulation of Gingival Fibroblast Interleukin-6 Secretion by Cyclosporine A, Journal of Periodontology, vol.70, issue.12, pp.1464-1471, 1999. ,
DOI : 10.1902/jop.1999.70.12.1464
The spliceosome: the most complex macromolecular machine in the cell?, BioEssays, vol.108, issue.12, pp.1147-1149, 2003. ,
DOI : 10.1002/bies.10394
Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506, Blood, vol.95, pp.2733-2741, 2000. ,
transcription by cyclosporine, FEBS Letters, vol.90, issue.2, pp.109-112, 1995. ,
DOI : 10.1016/0014-5793(94)01382-B
TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function, Annual Review of Immunology, vol.15, issue.1, pp.707-747, 1997. ,
DOI : 10.1146/annurev.immunol.15.1.707
Intrinsic differences between authentic and cryptic 5' splice sites, Nucleic Acids Research, vol.31, issue.21, pp.6321-6333, 2003. ,
DOI : 10.1093/nar/gkg830
URL : http://doi.org/10.1093/nar/gkg830
Gene Expression: The Close Coupling of Transcription and Splicing, Current Biology, vol.12, issue.9, pp.319-321, 2002. ,
DOI : 10.1016/S0960-9822(02)00829-1
The Impact of Immunosuppressive Drugs on the Analysis of T-Cell Activation, Current Medicinal Chemistry, vol.7, issue.7, pp.1-20, 2000. ,
DOI : 10.2174/0929867003374778
CREB: A Stimulus-Induced Transcription Factor Activated by A Diverse Array of Extracellular Signals, Annual Review of Biochemistry, vol.68, issue.1, pp.821-861, 1999. ,
DOI : 10.1146/annurev.biochem.68.1.821
-acting factors involved in the induced expresson of human IL-2 gene, Nucleic Acids Research, vol.17, issue.22, pp.9173-9184, 1989. ,
DOI : 10.1093/nar/17.22.9173
URL : https://hal.archives-ouvertes.fr/in2p3-01128037
): 2003 update, Human Mutation, vol.14, issue.6, pp.577-581, 2003. ,
DOI : 10.1002/humu.10212
Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation, The Lancet, vol.346, issue.8978, pp.796-798, 1995. ,
DOI : 10.1016/S0140-6736(95)91618-0
The Calcium/Calmodulin-dependent Protein Phosphatase Calcineurin Is the Major Elk-1 Phosphatase, Journal of Biological Chemistry, vol.272, issue.47, pp.29415-29418, 1997. ,
DOI : 10.1074/jbc.272.47.29415
Solution structure of the cyclosporin A/cyclophilin complex by NMR, Nature, vol.361, issue.6407, pp.88-91, 1993. ,
DOI : 10.1038/361088a0
Long-term benefits and risks of cyclosporin A (Sandimmun)?an analysis at 10 years, Transplant. Proc, vol.26, pp.2493-2498, 1994. ,
Protein Kinase C and Calcineurin Synergize to Activate I??B Kinase and NF-??B in T Lymphocytes, Journal of Biological Chemistry, vol.274, issue.33, pp.22923-22931, 1999. ,
DOI : 10.1074/jbc.274.33.22923
Cyclosporine A Upregulates Interleukin-6 Gene Expression in Human Gingiva: Possible Mechanism for Gingival Overgrowth, Journal of Periodontology, vol.65, issue.10, pp.895-903, 1994. ,
DOI : 10.1902/jop.1994.65.10.895
Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy., Molecular and Cellular Biology, vol.13, issue.8, pp.4513-4522, 1993. ,
DOI : 10.1128/MCB.13.8.4513
Distinct functions of SR proteins in alternative pre-mRNA splicing, Science, vol.260, issue.5105, pp.219-222, 1993. ,
DOI : 10.1126/science.8385799